Literature DB >> 15182901

The effect of Aloe vera A. Berger (Liliaceae) on gastric acid secretion and acute gastric mucosal injury in rats.

Sadiq Yusuf1, Abdulkarim Agunu, Mshelia Diana.   

Abstract

The effect of varying doses of ethanol extract of Aloe vera (Liliaceae) on acute gastric mucosal lesions induced by 0.6 M HCl and acid output was studied in the pylorus ligated and lumen perfuse rats, respectively. Acid secretion was determined by titration of the collected gastric juice to pH 7.0. Intraperitoneal injection of Aloe vera, dose dependently inhibited gastric acid secretion. The plant was more active as a gastroprotective agent at lower concentration against mucosal injury induced by 0.6 M HCl. In conclusion, Aloe vera is endowed with gastric acid anti-secretory activity and could protect the gastric mucosa at low concentrations against injurious agents.

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Year:  2004        PMID： 15182901     DOI： 10.1016/j.jep.2004.03.027

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  10 in total

1.  The effects of crude aqueous and alcohol extracts of Aloe vera on growth and abdominal viscera of suckling rats.

Authors:  Wabeya Beya; Bruce Davidson; Kennedy H Erlwanger
Journal:  Afr J Tradit Complement Altern Med       Date:  2012-07-01

2.  Development of bilayer floating tablet of amoxicillin and Aloe vera gel powder for treatment of gastric ulcers.

Authors:  Arati N Ranade; Sonali S Wankhede; Nisharani S Ranpise; Mayur S Mundada
Journal:  AAPS PharmSciTech       Date:  2012-11-08       Impact factor: 3.246

Review 3.  Potential prevention: Aloe vera mouthwash may reduce radiation-induced oral mucositis in head and neck cancer patients.

Authors:  Amirhossein Ahmadi
Journal:  Chin J Integr Med       Date:  2012-08-02       Impact factor: 1.978

4.  Effect of Hydro-alcoholic Extract of Persian Oak (Quercus brantii) in Experimentally Gastric Ulcer.

Authors:  Shahrzad Azizi; Abdollah Ghasemi Pirbalouti; Mahdi Amirmohammadi
Journal:  Iran J Pharm Res       Date:  2014       Impact factor: 1.696

5.  Medicinal Plants Used by Traditional Healers in Jordan, the Tafila Region.

Authors:  Abeer Abdelhalim; Talal Aburjai; Jane Hanrahan; Heba Abdel-Halim
Journal:  Pharmacogn Mag       Date:  2017-04-07       Impact factor: 1.085

Review 6.  Aloe Genus Plants: From Farm to Food Applications and Phytopharmacotherapy.

Authors:  Bahare Salehi; Sevil Albayrak; Hubert Antolak; Dorota Kręgiel; Ewelina Pawlikowska; Mehdi Sharifi-Rad; Yadav Uprety; Patrick Valere Tsouh Fokou; Zubaida Yousef; Zainul Amiruddin Zakaria; Elena Maria Varoni; Farukh Sharopov; Natália Martins; Marcello Iriti; Javad Sharifi-Rad
Journal:  Int J Mol Sci       Date:  2018-09-19       Impact factor: 5.923

Review 7.  Aloe vera at the frontier of glycobiology and integrative medicine: Health implications of an ancient plant.

Authors:  Peter Pressman; Roger Clemens; A Wallace Hayes
Journal:  SAGE Open Med       Date:  2019-09-13

8.  Gastroprotective Effect of Hydroalcoholic Extract of Aloe buettneri.

Authors:  Kossi Metowogo; Kwashie Eklu-Gadegbeku; Amégnona Agbonon; Kodjo A Aklikokou; Messanvi Gbeassor
Journal:  Iran J Pharm Res       Date:  2011       Impact factor: 1.696

9.  Study of Sedative-Hypnotic Effects of Aloe vera L. Aqueous Extract through Behavioral Evaluations and EEG Recording in Rats.

Authors:  Fatemeh Abdollahnejad; Mahmoud Mosaddegh; Sanaz Nasoohi; Javad Mirnajafi-Zadeh; Mohammad Kamalinejad; Mehrdad Faizi
Journal:  Iran J Pharm Res       Date:  2016       Impact factor: 1.696

Review 10.  Composition and applications of Aloe vera leaf gel.

Authors:  Josias H Hamman
Journal:  Molecules       Date:  2008-08-08       Impact factor: 4.411
  10 in total

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