Literature DB >> 15181021

The pediatric obesity epidemic: causes and controversies.

Arnold H Slyper1.   

Abstract

Obesity in children and adolescents has reached alarming proportions in the United States. Nutritional surveys do not indicate a significant increase in caloric intake in children and adolescents over the last 3 decades, although caloric intake has increased recently in adolescent females. Dietary fat has also been falling. There is no conclusive evidence linking physical inactivity to the obesity epidemic, and longitudinal studies indicate that physical inactivity may be the result of obesity rather than its cause. Hence, attention should be focused on dietary carbohydrate. Carbohydrate intake has increased as a result of the decrease in dietary fat. Indirect evidence also indicates that the quality of carbohydrate has been changing, so that American children are eating more carbohydrates with a higher glycemic index. It is proposed that high-glycemic-index diets lead to excessive weight gain as a consequence of postprandial hyperinsulinemia. Low-glycemic-index diets lower postprandial insulin levels and insulin resistance. It seems likely that diets restricted in sweetened sodas and noncitrus juices and containing ample whole grains, vegetables, and fruit could have a major impact on the prevalence of pediatric obesity.

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Year:  2004        PMID: 15181021     DOI: 10.1210/jc.2003-031449

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN: 0021-972X            Impact factor:   5.958


  26 in total

1.  Epigenomics: maternal high-fat diet exposure in utero disrupts peripheral circadian gene expression in nonhuman primates.

Authors:  Melissa Suter; Philip Bocock; Lori Showalter; Min Hu; Cynthia Shope; Robert McKnight; Kevin Grove; Robert Lane; Kjersti Aagaard-Tillery
Journal:  FASEB J       Date:  2010-11-19       Impact factor: 5.191

2.  Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome.

Authors:  Kjersti M Aagaard-Tillery; Kevin Grove; Jacalyn Bishop; Xingrao Ke; Qi Fu; Robert McKnight; Robert H Lane
Journal:  J Mol Endocrinol       Date:  2008-05-30       Impact factor: 5.098

3.  Contributors to Pediatric Obesity in Adolescence: More than just Energy Imbalance.

Authors:  Michelle Cardel; Akilah Dulin-Keita; Krista Casazza
Journal:  Open Obes J       Date:  2011

4.  Factors associated with early platelet activation in obese children.

Authors:  Anel Gómez García; Guillermina García Núñez; Martha Eva Viveros Sandoval; Sergio Gutierrez Castellanos; Cleto Alvarez Aguilar
Journal:  Clin Med Res       Date:  2014-01-10

5.  Platelet activity in Chinese obese adolescents with and without insulin resistance.

Authors:  Huimin Lu; Shundong Lei; Jiuming Zhao; Ni Chen
Journal:  J Thromb Thrombolysis       Date:  2014       Impact factor: 2.300

6.  Whole-body vibration slows the acquisition of fat in mature female rats.

Authors:  G F Maddalozzo; U T Iwaniec; R T Turner; C J Rosen; J J Widrick
Journal:  Int J Obes (Lond)       Date:  2008-07-29       Impact factor: 5.095

7.  Dietary glycemic index, development of islet autoimmunity, and subsequent progression to type 1 diabetes in young children.

Authors:  Molly M Lamb; Xiang Yin; Katherine Barriga; Michelle R Hoffman; Anna E Barón; George S Eisenbarth; Marian Rewers; Jill M Norris
Journal:  J Clin Endocrinol Metab       Date:  2008-08-05       Impact factor: 5.958

Review 8.  Central leptin gene therapy ameliorates diabetes type 1 and 2 through two independent hypothalamic relays; a benefit beyond weight and appetite regulation.

Authors:  Satya P Kalra
Journal:  Peptides       Date:  2009-08-06       Impact factor: 3.750

9.  Is C-reactive protein a reliable test for suspected appendicitis in extremely obese children?

Authors:  Balazs Kutasy; Ganapathy Laxamanadass; Prem Puri
Journal:  Pediatr Surg Int       Date:  2010-01       Impact factor: 1.827

10.  Prevalence of overweight and obesity in Sardinian adolescents.

Authors:  F Velluzzi; A Lai; G Secci; R Mastinu; A Pilleri; R Cabula; E Rizzolo; P L Cocco; D Fadda; F Binaghi; S Mariotti; A Loviselli
Journal:  Eat Weight Disord       Date:  2007-06       Impact factor: 4.652

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