Literature DB >> 15180509

Antiviral activity of ribosome inactivating proteins in medicine.

Bijal A Parikh1, Nilgun E Tumer.   

Abstract

Pokeweed antiviral protein and several other ribosome inactivating proteins are effective against a broad range of viruses. Recent results have shown that their enzymatic activity is not limited to depurination of the large rRNA, they can depurinate other nucleic acids, including viral RNAs. Antiviral activity of RIPs is summarized here in light of their novel activities and recent developments in the field.

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Year:  2004        PMID： 15180509     DOI： 10.2174/1389557043403800

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  33 in total

1.  BDP-30, a systemic resistance inducer from Boerhaavia diffusa L., suppresses TMV infection, and displays homology with ribosome-inactivating proteins.

Authors:  Shalini Srivastava; H N Verma; Aparana Srivastava; Vivek Prasad
Journal:  J Biosci       Date:  2015-03       Impact factor: 1.826

Review 2.  Interaction of ricin and Shiga toxins with ribosomes.

Authors:  Nilgun E Tumer; Xiao-Ping Li
Journal:  Curr Top Microbiol Immunol       Date:  2012       Impact factor: 4.291

3.  Trichosanthin inhibits integration of human immunodeficiency virus type 1 through depurinating the long-terminal repeats.

Authors:  Wen-Long Zhao; Du Feng; Ju Wu; Sen-Fang Sui
Journal:  Mol Biol Rep       Date:  2009-08-11       Impact factor: 2.316

4.  Vinyldeoxyadenosine in a sarcin-ricin RNA loop and its binding to ricin toxin a-chain.

Authors:  Setu Roday; Suwipa Saen-oon; Vern L Schramm
Journal:  Biochemistry       Date:  2007-05-04       Impact factor: 3.162

5.  Inhibition of hepatitis B virus replication by pokeweed antiviral protein in vitro.

Authors:  Yong-Wen He; Chun-Xia Guo; Yan-Feng Pan; Cheng Peng; Zhi-Hong Weng
Journal:  World J Gastroenterol       Date:  2008-03-14       Impact factor: 5.742

6.  Alpha-momorcharin, a RIP produced by bitter melon, enhances defense response in tobacco plants against diverse plant viruses and shows antifungal activity in vitro.

Authors:  Feng Zhu; Ping Zhang; Yan-Fa Meng; Fei Xu; Da-Wei Zhang; Jian Cheng; Hong-Hui Lin; De-Hui Xi
Journal:  Planta       Date:  2012-09-16       Impact factor: 4.116

7.  Stress-induced curcin-L promoter in leaves of Jatropha curcas L. and characterization in transgenic tobacco.

Authors:  Xiaobo Qin; Xiaojiang Zheng; Caixia Shao; Jihai Gao; Luding Jiang; Xunlu Zhu; Fang Yan; Lin Tang; Ying Xu; Fang Chen
Journal:  Planta       Date:  2009-05-28       Impact factor: 4.116

8.  The diphthamide modification on elongation factor-2 renders mammalian cells resistant to ricin.

Authors:  Pradeep K Gupta; Shihui Liu; Mariska P Batavia; Stephen H Leppla
Journal:  Cell Microbiol       Date:  2008-05-05       Impact factor: 3.715

9.  Generation of pokeweed antiviral protein mutations in Saccharomyces cerevisiae: evidence that ribosome depurination is not sufficient for cytotoxicity.

Authors:  Katalin A Hudak; Bijal A Parikh; Rong Di; Marianne Baricevic; Maria Santana; Mirjana Seskar; Nilgun E Tumer
Journal:  Nucleic Acids Res       Date:  2004-08-10       Impact factor: 16.971

10.  Transition State Structure of RNA Depurination by Saporin L3.

Authors:  Hongling Yuan; Christopher F Stratton; Vern L Schramm
Journal:  ACS Chem Biol       Date:  2016-03-08       Impact factor: 5.100
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