Mason C Leung1, Gabriel Y Ng, K K Yip. 1. Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China. rsmcpleung@inet.polyu.edu.hk
Abstract
OBJECTIVE: To evaluate the effect of therapeutic ultrasound on the acute inflammation of soft-tissue injuries by measuring the levels of prostaglandin E(2) (PGE(2)) and leukotriene B(4) (LTB(4)). DESIGN: Randomized, case-control study. SETTING: Laboratory animal facility. ANIMALS: Thirty 3-month-old male Sprague-Dawley rats. INTERVENTION: Rats with medial collateral ligament transection were given 5 minutes of pulsed ultrasound therapy (1:4) daily, with different durations (1, 5, 10d) and intensities (0, 0.5, 1.5, 2.3W/cm(2)). MAIN OUTCOME MEASURES: Levels of PGE(2) and LTB(4). RESULTS: The levels of PGE(2) and LTB(4) were higher in all intensity subgroups that received 2.3W/cm(2) intensity on postinjury day 2. On postinjury day 11, LTB(4) was significantly decreased, but PGE(2) was significantly increased. CONCLUSIONS: Pulsed ultrasound therapy may stimulate inflammation of acute ligament injury.
OBJECTIVE: To evaluate the effect of therapeutic ultrasound on the acute inflammation of soft-tissue injuries by measuring the levels of prostaglandin E(2) (PGE(2)) and leukotriene B(4) (LTB(4)). DESIGN: Randomized, case-control study. SETTING: Laboratory animal facility. ANIMALS: Thirty 3-month-old male Sprague-Dawley rats. INTERVENTION: Rats with medial collateral ligament transection were given 5 minutes of pulsed ultrasound therapy (1:4) daily, with different durations (1, 5, 10d) and intensities (0, 0.5, 1.5, 2.3W/cm(2)). MAIN OUTCOME MEASURES: Levels of PGE(2) and LTB(4). RESULTS: The levels of PGE(2) and LTB(4) were higher in all intensity subgroups that received 2.3W/cm(2) intensity on postinjury day 2. On postinjury day 11, LTB(4) was significantly decreased, but PGE(2) was significantly increased. CONCLUSIONS: Pulsed ultrasound therapy may stimulate inflammation of acute ligament injury.
Authors: A Burke Gurney; Daniel Wascher; Robert Schenck; Alexandria Tennison; Bettina Jaramillo Journal: Sports Health Date: 2011-07 Impact factor: 3.843
Authors: Wouber Herickson de Brito Vieira; Kardec Alecxandro Aguiar; Kimberly Moreira da Silva; Pablo Miranda Canela; Flávio Santos da Silva; Bento João Abreu Journal: Crit Ultrasound J Date: 2012-05-28