Literature DB >> 15179467

A high-throughput NMR-based ee-assay using chemical shift imaging.

Manfred T Reetz1, Patrick Tielmann, Andreas Eipper, Alfred Ross, Gotz Schlotterbeck.   

Abstract

The throughput of a previously described NMR-based -assay has been increased by a factor of at least 4 as a consequence of adapting the system to chemical shift imaging; by using a 19-capillary system the enantiomeric purity of 5600 samples can be measured per day.

Year:  2004        PMID： 15179467     DOI： 10.1039/b403249g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  Assessment of inhibitory potency of antibiotics by MRI: apparent T2 as a marker of cell growth.

Authors:  Verena Hoerr; Kerstin Hoffmann; Curd Schollmayer; Ulrike Holzgrabe; Axel Haase; Peter Jakob; Cornelius Faber
Journal:  MAGMA       Date:  2006-11-10       Impact factor: 2.310

2.  "Cassette" in situ enzymatic screening identifies complementary chiral scaffolds for hydrolytic kinetic resolution across a range of epoxides.

Authors:  Sangeeta Dey; Douglas R Powell; Chunhua Hu; David B Berkowitz
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

3.  An ESI-MS method to determine yield and enantioselectivity in a single assay.

Authors:  Maureen E Smith; Steven A Knolls; MyLe Thompson; Douglas S Masterson
Journal:  J Am Soc Mass Spectrom       Date:  2014-12-16       Impact factor: 3.109

4.  High-throughput screening of chemical exchange saturation transfer MR contrast agents.

Authors:  Guanshu Liu; Assaf A Gilad; Jeff W M Bulte; Peter C M van Zijl; Michael T McMahon
Journal:  Contrast Media Mol Imaging       Date:  2010 May-Jun       Impact factor: 3.161

5.  Combinatorial catalysis employing a visible enzymatic beacon in real time: synthetically versatile (pseudo)halometalation/carbocyclizations.

Authors:  Jacob A Friest; Sylvain Broussy; Woo Jin Chung; David B Berkowitz
Journal:  Angew Chem Int Ed Engl       Date:  2011-08-16       Impact factor: 15.336
  5 in total

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