Literature DB >> 15179064

Metastatic neuroblastoma presenting with binocular blindness from intracranial compression of the optic nerves.

Juan J Chan Lau1, Jonathan D Trobe, Robert E Ruiz, Robert W Cho, Daniel S Wechsler, Gaurang V Shah, Stephen S Gebarski.   

Abstract

A 2-year-old boy with blindness as an isolated symptom was found to have no light perception binocularly because of compression of both optic nerves by a neuroblastoma infiltrating the walls of the optic canals and medial sphenoid bone. Imaging disclosed a primary tumor near the kidney and multiple osseous metastases. Although neuroblastoma commonly causes blindness by metastasis to the orbit, it rarely causes bilateral blindness from intracranial compression of the optic nerves. This is the first report of bilateral blindness as the presenting feature.

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Year:  2004        PMID: 15179064     DOI: 10.1097/00041327-200406000-00005

Source DB:  PubMed          Journal:  J Neuroophthalmol        ISSN: 1070-8022            Impact factor:   3.042


  2 in total

Review 1.  Neuroblastoma in childhood: review and radiological findings.

Authors:  Georgia Papaioannou; Kieran McHugh
Journal:  Cancer Imaging       Date:  2005-09-30       Impact factor: 3.909

Review 2.  Staging of common paediatric tumours.

Authors:  Hervé J Brisse
Journal:  Pediatr Radiol       Date:  2009-06
  2 in total

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