Literature DB >> 15178399

Synthesis of 2-[(2-pyridyl)amino]ethyl beta-D-lactosaminide and evaluation of its acceptor ability for sialyltransferase: a comparison with 4-methylumbelliferyl and dansyl beta-D-lactosaminide.

Yasuhiro Kajihara1, Daisuke Kamiyama, Naoki Yamamoto, Tohru Sakakibara, Masayuki Izumi, Hironobu Hashimoto.   

Abstract

We reported the synthesis of beta-D-lactosaminide with a 2-aminopyridyl group that is linked to a glycosyl tether at the reducing end. This fluorescent disaccharide acts as an acceptor for both alpha-(2-->6)- and alpha-(2-->3)-sialyltransferases. In addition, the acceptor ability of this disaccharide was evaluated and compared with that of beta-D-lactosaminide having a dansyl or a 4-methylumbelliferyl group. Copyright 2004 Elsevier Ltd.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15178399     DOI： 10.1016/j.carres.2004.03.015

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN： 0008-6215            Impact factor:   2.104


  7 in total

1.  N-Terminal 112 amino acid residues are not required for the sialyltransferase activity of Photobacterium damsela alpha2,6-sialyltransferase.

Authors:  Mingchi Sun; Yanhong Li; Harshal A Chokhawala; Ryan Henning; Xi Chen
Journal:  Biotechnol Lett       Date:  2007-11-08       Impact factor: 2.461

2.  Identifying selective inhibitors against the human cytosolic sialidase NEU2 by substrate specificity studies.

Authors:  Yanhong Li; Hongzhi Cao; Hai Yu; Yi Chen; Kam Lau; Jingyao Qu; Vireak Thon; Go Sugiarto; Xi Chen
Journal:  Mol Biosyst       Date:  2011-01-04

3.  Versatile strategy for the synthesis of biotin-labelled glycans, their immobilization to establish a bioactive surface and interaction studies with a lectin on a biochip.

Authors:  F Javier Muñoz; Angel Rumbero; José V Sinisterra; J Ignacio Santos; Sabine André; Hans-J Gabius; Jesús Jiménez-Barbero; María J Hernáiz
Journal:  Glycoconj J       Date:  2008-03-18       Impact factor: 2.916

4.  Trans-sialidase activity of Photobacterium damsela alpha2,6-sialyltransferase and its application in the synthesis of sialosides.

Authors:  Jiansong Cheng; Shengshu Huang; Hai Yu; Yanhong Li; Kam Lau; Xi Chen
Journal:  Glycobiology       Date:  2009-10-30       Impact factor: 4.313

5.  The Hd0053 gene of Haemophilus ducreyi encodes an alpha2,3-sialyltransferase.

Authors:  Yanhong Li; Mingchi Sun; Shengshu Huang; Hai Yu; Harshal A Chokhawala; Vireak Thon; Xi Chen
Journal:  Biochem Biophys Res Commun       Date:  2007-07-23       Impact factor: 3.575

6.  Multifunctionality of Campylobacter jejuni sialyltransferase CstII: characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities.

Authors:  Jiansong Cheng; Hai Yu; Kam Lau; Shengshu Huang; Harshal A Chokhawala; Yanhong Li; Vinod Kumar Tiwari; Xi Chen
Journal:  Glycobiology       Date:  2008-05-28       Impact factor: 4.313

7.  A sialyltransferase mutant with decreased donor hydrolysis and reduced sialidase activities for directly sialylating LewisX.

Authors:  Go Sugiarto; Kam Lau; Jingyao Qu; Yanhong Li; Sunghyuk Lim; Shengmao Mu; James B Ames; Andrew J Fisher; Xi Chen
Journal:  ACS Chem Biol       Date:  2012-05-14       Impact factor: 5.100
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.