Literature DB >> 15178315

Structural commonalities among integral membrane enzymes.

Michael H Bracey1, Benjamin F Cravatt, Raymond C Stevens.   

Abstract

The X-ray crystal structures of five distinct enzymes (prostaglandin H(2) synthase, squalene cyclase, fatty acid amide hydrolase, microsomal cytochrome P450, and estrone sulfatase) challenge contemporary descriptions of integral membrane proteins. This structurally divergent group represents an important component of the integral membrane proteome that lies at the bilayer's aqueous interface. We summarize here what is collectively understood about the membrane insertion of these proteins, what roles they may play in lipid biology, and their relationship to soluble structural homologs.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15178315     DOI： 10.1016/j.febslet.2004.04.084

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  25 in total

Review 1.  Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis.

Authors:  William L Smith; Yoshihiro Urade; Per-Johan Jakobsson
Journal:  Chem Rev       Date:  2011-09-27       Impact factor: 60.622

2.  Cluster formation of anchored proteins induced by membrane-mediated interaction.

Authors:  Shuangyang Li; Xianren Zhang; Wenchuan Wang
Journal:  Biophys J       Date:  2010-06-02       Impact factor: 4.033

3.  Hybrid homology modeling and mutational analysis of cytochrome P450C24A1 (CYP24A1) of the Vitamin D pathway: insights into substrate specificity and membrane bound structure-function.

Authors:  Andrew J Annalora; Ekaterina Bobrovnikov-Marjon; Rita Serda; Andrzej Pastuszyn; Sandra E Graham; Craig B Marcus; John L Omdahl
Journal:  Arch Biochem Biophys       Date:  2006-12-03       Impact factor: 4.013

4.  Compound heterozygosity of novel missense mutations in the gamma-glutamyl-carboxylase gene causes hereditary combined vitamin K-dependent coagulation factor deficiency.

Authors:  Dhouha Darghouth; Kevin W Hallgren; Rebecca L Shtofman; Amel Mrad; Youssef Gharbi; Ahmed Maherzi; Radhia Kastally; Sophie LeRicousse; Kathleen L Berkner; Jean-Philippe Rosa
Journal:  Blood       Date:  2006-05-23       Impact factor: 22.113

Review 5.  Chemistry of the retinoid (visual) cycle.

Authors:  Philip D Kiser; Marcin Golczak; Krzysztof Palczewski
Journal:  Chem Rev       Date:  2013-07-11       Impact factor: 60.622

6.  Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis.

Authors:  Philip D Kiser; Erik R Farquhar; Wuxian Shi; Xuewu Sui; Mark R Chance; Krzysztof Palczewski
Journal:  Proc Natl Acad Sci U S A       Date:  2012-09-24       Impact factor: 11.205

7.  Identification of a novel N-terminal hydrophobic sequence that targets proteins to lipid droplets.

Authors:  John K Zehmer; René Bartz; Pingsheng Liu; Richard G W Anderson
Journal:  J Cell Sci       Date:  2008-05-13       Impact factor: 5.285

Review 8.  New insights into type II NAD(P)H:quinone oxidoreductases.

Authors:  Ana M P Melo; Tiago M Bandeiras; Miguel Teixeira
Journal:  Microbiol Mol Biol Rev       Date:  2004-12       Impact factor: 11.056

9.  Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism.

Authors:  Andrew J Annalora; David B Goodin; Wen-Xu Hong; Qinghai Zhang; Eric F Johnson; C David Stout
Journal:  J Mol Biol       Date:  2009-12-01       Impact factor: 5.469

10.  Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis.

Authors:  Justin T Marinko; Hui Huang; Wesley D Penn; John A Capra; Jonathan P Schlebach; Charles R Sanders
Journal:  Chem Rev       Date:  2019-01-04       Impact factor: 60.622
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.