Literature DB >> 15177543

Medical management of postoperative recurrence in Crohn's disease.

Gert Van Assche1, Paul Rutgeerts.   

Abstract

More than half of Crohn's disease patients require surgery during the course of their disease. Although endoscopic recurrence does not necessarily imply that patients have symptom recurrence, the high need for repeated surgery indicates that lesions gradually developing after surgical remission lead to fibrostenosis or other complications. Despite multiple clinical trials a clear medical strategy to prevent disease recurrence has not been identified. Future well designed collaborative trials with specified end points are needed to optimize clinical practice in the prevention of postoperative Crohn's disease recurrence.

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Year:  2004        PMID： 15177543     DOI： 10.1016/j.gtc.2004.02.012

Source DB:  PubMed          Journal:  Gastroenterol Clin North Am        ISSN： 0889-8553            Impact factor:   3.806


  7 in total

1.  Anti-Saccharomyces cerevisiae antibodies associate with phenotypes and higher risk for surgery in Crohn's disease: a meta-analysis.

Authors:  Zhaoxia Zhang; Chen Li; Xinmei Zhao; Chaolan Lv; Qiong He; Shan Lei; Yandong Guo; Fachao Zhi
Journal:  Dig Dis Sci       Date:  2012-06-06       Impact factor: 3.199

2.  Serial intralesional injections of infliximab in small bowel Crohn's strictures are feasible and might lower inflammation.

Authors:  Jakob Hendel; John Gásdal Karstensen; Peter Vilmann
Journal:  United European Gastroenterol J       Date:  2014-10       Impact factor: 4.623

3.  Impact of balloon-assisted enteroscopy on the diagnosis and management of suspected and established small-bowel Crohn's disease.

Authors:  Udayakumar Navaneethan; John J Vargo; K V Narayanan Menon; Madhusudhan R Sanaka; Chung-Jyi Tsai
Journal:  Endosc Int Open       Date:  2014-11-12

4.  Mercaptopurine versus placebo to prevent recurrence of Crohn's disease after surgical resection (TOPPIC): a multicentre, double-blind, randomised controlled trial.

Authors:  Craig Mowat; Ian Arnott; Aiden Cahill; Malcolm Smith; Tariq Ahmad; Sreedhar Subramanian; Simon Travis; John Morris; John Hamlin; Anjan Dhar; Chuka Nwokolo; Cathryn Edwards; Tom Creed; Stuart Bloom; Mohamed Yousif; Linzi Thomas; Simon Campbell; Stephen J Lewis; Shaji Sebastian; Sandip Sen; Simon Lal; Chris Hawkey; Charles Murray; Fraser Cummings; Jason Goh; James O Lindsay; Naila Arebi; Lindsay Potts; Aileen J McKinley; John M Thomson; John A Todd; Mhairi Collie; Malcolm G Dunlop; Ashley Mowat; Daniel R Gaya; Jack Winter; Graham D Naismith; Holly Ennis; Catriona Keerie; Steff Lewis; Robin J Prescott; Nicholas A Kennedy; Jack Satsangi
Journal:  Lancet Gastroenterol Hepatol       Date:  2016-08-30

Review 5.  Pathophysiology of Crohn's disease inflammation and recurrence.

Authors:  L Petagna; A Antonelli; C Ganini; V Bellato; M Campanelli; A Divizia; C Efrati; M Franceschilli; A M Guida; S Ingallinella; F Montagnese; B Sensi; L Siragusa; G S Sica
Journal:  Biol Direct       Date:  2020-11-07       Impact factor: 4.540

6.  Dysbiosis and relapse-related microbiome in inflammatory bowel disease: A shotgun metagenomic approach.

Authors:  Gerard Serrano-Gómez; Luis Mayorga; Iñigo Oyarzun; Joaquim Roca; Natalia Borruel; Francesc Casellas; Encarna Varela; Marta Pozuelo; Kathleen Machiels; Francisco Guarner; Severine Vermeire; Chaysavanh Manichanh
Journal:  Comput Struct Biotechnol J       Date:  2021-12-02       Impact factor: 7.271

7.  Early Postoperative Endoscopic Recurrence in Crohn's Disease Is Characterised by Distinct Microbiota Recolonisation.

Authors:  Kathleen Machiels; Marta Pozuelo Del Río; Adrian Martinez-De la Torre; Zixuan Xie; Victòria Pascal Andreu; João Sabino; Alba Santiago; David Campos; Albert Wolthuis; André D'Hoore; Gert De Hertogh; Marc Ferrante; Chaysavanh Manichanh; Séverine Vermeire
Journal:  J Crohns Colitis       Date:  2020-11-07       Impact factor: 9.071
  7 in total

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