Literature DB >> 15176723

Memory development and intellectual disabilities.

S Vicari1.   

Abstract

Neuropsychological research has permitted different cognitive profiles among subjects with intellectual disabilities (ID) of different etiology to be defined. For example, numerous authors have stressed that the typical language profile for people with Down's syndrome (DS) consists of poor production with greater compromise of morphosyntax than of lexical abilities, but relatively preserved comprehension. Children with Williams' syndrome (WS) often show marked impairment in certain visuospatial abilities (especially praxic-constructive) and relative preservation of both productive and receptive language, at least concerning the phonological elements. These observations seem to support a theoretical approach that considers ID not as a mere slowing of normal cognitive development, but as distinct, individual profiles that can be qualitatively specified. The importance of this approach was shown in several recent studies of memory, especially implicit memory in subjects with ID. Neuropsychological studies suggest insufficient development of the mnemic function in ID at different levels of articulation. Long-term memory has been extensively investigated in people with ID both in the explicit and in the implicit component. According to recent studies, people with ID should show a diffuse impairment of declarative mnesic abilities and a relative preservation of implicit memory. The focus of this study is on the characteristics of long- and short-term memory in children with ID and, particularly, with DS and WS. The results are relevant to knowledge on the qualitative aspects of the anomalous cognitive development in mentally retarded people and the neurobiological substrate underlying this development.

Entities:  

Mesh:

Year:  2004        PMID: 15176723     DOI: 10.1111/j.1651-2227.2004.tb03059.x

Source DB:  PubMed          Journal:  Acta Paediatr Suppl        ISSN: 0803-5326


  7 in total

1.  Speech Characteristics and Intelligibility in Adults with Mild and Moderate Intellectual Disabilities.

Authors:  Marjolein C Coppens-Hofman; Hayo Terband; Ad F M Snik; Ben A M Maassen
Journal:  Folia Phoniatr Logop       Date:  2017-01-25       Impact factor: 0.849

2.  Lifespan analysis of brain development, gene expression and behavioral phenotypes in the Ts1Cje, Ts65Dn and Dp(16)1/Yey mouse models of Down syndrome.

Authors:  Nadine M Aziz; Faycal Guedj; Jeroen L A Pennings; Jose Luis Olmos-Serrano; Ashley Siegel; Tarik F Haydar; Diana W Bianchi
Journal:  Dis Model Mech       Date:  2018-06-12       Impact factor: 5.758

3.  The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome.

Authors:  Arnaud Duchon; Stéphanie Pothion; Véronique Brault; Andrew J Sharp; Victor L J Tybulewicz; Elizabeth M C Fisher; Yann Herault
Journal:  Behav Brain Res       Date:  2010-10-31       Impact factor: 3.332

Review 4.  Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities.

Authors:  Noemí Rueda; Jesús Flórez; Carmen Martínez-Cué
Journal:  Neural Plast       Date:  2012-05-22       Impact factor: 3.599

5.  Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome.

Authors:  Martina Parrini; Diego Ghezzi; Gabriele Deidda; Lucian Medrihan; Enrico Castroflorio; Micol Alberti; Pietro Baldelli; Laura Cancedda; Andrea Contestabile
Journal:  Sci Rep       Date:  2017-12-04       Impact factor: 4.379

Review 6.  The GABAergic Hypothesis for Cognitive Disabilities in Down Syndrome.

Authors:  Andrea Contestabile; Salvatore Magara; Laura Cancedda
Journal:  Front Cell Neurosci       Date:  2017-03-07       Impact factor: 5.505

Review 7.  Intellectual disability and autism spectrum disorders 'on the fly': insights from Drosophila.

Authors:  Mireia Coll-Tané; Alina Krebbers; Anna Castells-Nobau; Christiane Zweier; Annette Schenck
Journal:  Dis Model Mech       Date:  2019-05-13       Impact factor: 5.758

  7 in total

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