Literature DB >> 15175782

An unusual cause of pulmonary haemorrhage in a patient with rheumatoid arthritis.

M S Koh1, P H Leng, P Eng, J Hwang.   

Abstract

INTRODUCTION: Pulmonary haemorrhage is a rare presentation of strongyloides hyperinfection. CLINICAL PICTURE: A 69-year-old female patient with rheumatoid arthritis on methotrexate and prednisolone presented with severe community acquired pneumonia. Intravenous trimethoprim/ sulfamethoxazole (bactrim) and high dose hydrocortisone for Pneumocystis carinii pneumonia were commenced. She developed pulmonary haemorrhage 2 weeks later and bronchoalveolar lavage cytology revealed helminthic larvae identified as strongyloides. TREATMENT AND OUTCOME: Despite treatment with ivermectin and albendazole with rapid tailing down of hydrocortisone, she succumbed to her illness.
CONCLUSIONS: Strongyloides hyperinfection should be considered in an immunocompromised patient on high dose corticosteroid presenting with pulmonary haemorrhage. Prognosis remains dismal as supported by our case report and current literature.

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Year:  2004        PMID: 15175782

Source DB:  PubMed          Journal:  Ann Acad Med Singapore        ISSN: 0304-4602            Impact factor:   2.473


  4 in total

Review 1.  Strongyloides stercoralis infection in a patient with rheumatoid arthritis and type 2 diabetes mellitus: a case-based review.

Authors:  Alireza Ashiri; Molouk Beiromvand; Abdollah Khanzadeh
Journal:  Clin Rheumatol       Date:  2019-05-23       Impact factor: 2.980

2.  Co-infection with Nocardia asteroides complex and Strongyloides stercoralis in a patient with autoimmune hemolytic anemia.

Authors:  I Praharaj; S Sujatha; M A Ashwini; S C Parija
Journal:  Infection       Date:  2013-08-08       Impact factor: 3.553

3.  Airway bleed after percutaneous tracheostomy is not always procedure-related.

Authors:  Vijaya P Patil; Amit Singhal; C S Pramesh
Journal:  Indian J Crit Care Med       Date:  2009 Apr-Jun

Review 4.  Severe strongyloidiasis: a systematic review of case reports.

Authors:  Dora Buonfrate; Ana Requena-Mendez; Andrea Angheben; Jose Muñoz; Federico Gobbi; Jef Van Den Ende; Zeno Bisoffi
Journal:  BMC Infect Dis       Date:  2013-02-08       Impact factor: 3.090

  4 in total

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