Literature DB >> 15175626

Constitutive activation of PI3K is involved in the spontaneous proliferation of primary acute myeloid leukemia cells: direct evidence of PI3K activation.

Y Kubota, H Ohnishi, A Kitanaka, T Ishida, T Tanaka.   

Abstract

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Year:  2004        PMID： 15175626     DOI： 10.1038/sj.leu.2403402

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  18 in total

1.  A Phase I/II Study of the mTOR Inhibitor Everolimus in Combination with HyperCVAD Chemotherapy in Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia.

Authors:  Naval Daver; Yanis Boumber; Hagop Kantarjian; Farhad Ravandi; Jorge Cortes; Michael E Rytting; Jitesh D Kawedia; Jordan Basnett; Kirk S Culotta; Zhihong Zeng; Hongbo Lu; Mary Ann Richie; Rebecca Garris; Lianchun Xiao; Wenbin Liu; Keith A Baggerly; Elias Jabbour; Susan O'Brien; Jan Burger; Linda J Bendall; Deborah Thomas; Marina Konopleva
Journal:  Clin Cancer Res       Date:  2015-02-27       Impact factor: 12.531

2.  mTOR regulates cell survival after etoposide treatment in primary AML cells.

Authors:  Qing Xu; James E Thompson; Martin Carroll
Journal:  Blood       Date:  2005-09-08       Impact factor: 22.113

3.  Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance.

Authors:  James A McCubrey; Linda S Steelman; Richard A Franklin; Steven L Abrams; William H Chappell; Ellis W T Wong; Brian D Lehmann; David M Terrian; Jorg Basecke; Franca Stivala; Massimo Libra; Camilla Evangelisti; Alberto M Martelli
Journal:  Adv Enzyme Regul       Date:  2007-03-26

4.  Synergistic effects of phenylhexyl isothiocyanate and LY294002 on the PI3K/Akt signaling pathway in HL-60 cells.

Authors:  Huicong Yang; Yiqun Huang; Yong Zou; Xudong Ma
Journal:  Oncol Lett       Date:  2017-07-08       Impact factor: 2.967

5.  MK-2206 induces apoptosis of AML cells and enhances the cytotoxicity of cytarabine.

Authors:  Jeng-Wei Lu; Yu-Min Lin; Yen-Ling Lai; Chien-Yuan Chen; Chung-Yi Hu; Hwei-Fang Tien; Da-Liang Ou; Liang-In Lin
Journal:  Med Oncol       Date:  2015-06-19       Impact factor: 3.064

6.  Significance of heat-shock protein (HSP) 90 expression in acute myeloid leukemia cells.

Authors:  Pascale Flandrin; Denis Guyotat; Amélie Duval; Jérôme Cornillon; Emmanuelle Tavernier; Nathalie Nadal; Lydia Campos
Journal:  Cell Stress Chaperones       Date:  2008-04-03       Impact factor: 3.667

Review 7.  Exploiting signal transduction pathways in acute myelogenous leukemia.

Authors:  Alexander E Perl; Martin Carroll
Journal:  Curr Treat Options Oncol       Date:  2007-08

8.  HGF/c-met system targeting PI3K/AKT and STAT3/phosphorylated-STAT3 pathways in pituitary adenomas: an immunohistochemical characterization in view of targeted therapies.

Authors:  Maria Trovato; Maria Luisa Torre; Marta Ragonese; Angela Simone; Rosy Scarfì; Valeria Barresi; Giuseppe Giuffrè; Salvatore Benvenga; Flavio F Angileri; Giovanni Tuccari; Francesco Trimarchi; Rosaria Maddalena Ruggeri; Salvatore Cannavò
Journal:  Endocrine       Date:  2013-04-11       Impact factor: 3.633

Review 9.  Novel postremission strategies in adults with acute myeloid leukemia.

Authors:  Jeffrey E Lancet; Judith E Karp
Journal:  Curr Opin Hematol       Date:  2009-03       Impact factor: 3.284

10.  Bone marrow mesenchymal stem cells from leukemia patients inhibit growth and apoptosis in serum-deprived K562 cells.

Authors:  Zhaohui Wei; Naiyao Chen; Hongxing Guo; Xueming Wang; Fangyun Xu; Qian Ren; ShiHong Lu; Bin Liu; Lei Zhang; Hui Zhao
Journal:  J Exp Clin Cancer Res       Date:  2009-11-03
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