Literature DB >> 15174849

Antifungal cyclopentenediones from Piper coruscans.

Xing-Cong Li1, Daneel Ferreira, Melissa R Jacob, Qifeng Zhang, Shabana I Khan, Hala N ElSohly, Dale G Nagle, Troy J Smillie, Ikhlas A Khan, Larry A Walker, Alice M Clark.   

Abstract

Coruscanones A and B, two new antifungal cyclopentenedione derivatives, have been isolated from Piper coruscans and their structures elucidated by spectroscopic and chemical methods. Coruscanone A exhibits significant antifungal activity against Candida albicans and its azole-resistant strains and may serve as a template for a new class of antifungal agents.

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Year:  2004        PMID： 15174849     DOI： 10.1021/ja048081c

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  7 in total

1.  Capisterones A and B, which enhance fluconazole activity in Saccharomyces cerevisiae, from the marine green alga Penicillus capitatus.

Authors:  Xing-Cong Li; Melissa R Jacob; Yuanqing Ding; Ameeta K Agarwal; Troy J Smillie; Shabana I Khan; Dale G Nagle; Daneel Ferreira; Alice M Clark
Journal:  J Nat Prod       Date:  2006-04       Impact factor: 4.050

2.  Natural Product Based 6-Hydroxy-2,3,4,6-tetrahydropyrrolo[1,2-a]pyrimidinium Scaffold as A New Antifungal Template.

Authors:  Xing-Cong Li; K Suresh Babu; Melissa R Jacob; Shabana I Khan; Ameeta K Agarwal; Alice M Clark
Journal:  ACS Med Chem Lett       Date:  2011-05-12       Impact factor: 4.345

3.  Synthesis, antifungal activity, and structure-activity relationships of coruscanone A analogues.

Authors:  K Suresh Babu; Xing-Cong Li; Melissa R Jacob; Qifeng Zhang; Shabana I Khan; Daneel Ferreira; Alice M Clark
Journal:  J Med Chem       Date:  2006-12-28       Impact factor: 7.446

4.  Protocol for Identifying Natural Agents That Selectively Affect Adhesion, Thickness, Architecture, Cellular Phenotypes, Extracellular Matrix, and Human White Blood Cell Impenetrability of Candida albicans Biofilms.

Authors:  Yang-Nim Park; Thyagarajan Srikantha; Karla J Daniels; Melissa R Jacob; Ameeta K Agarwal; Xing-Cong Li; David R Soll
Journal:  Antimicrob Agents Chemother       Date:  2017-10-24       Impact factor: 5.191

5.  Antifungal Compounds from Piper Species.

Authors:  Wen-Hui Xu; Xing-Cong Li
Journal:  Curr Bioact Compd       Date:  2011-12

6.  Chemical and Enantioselective Analysis of the Leaf Essential Oil from Piper coruscans Kunth (Piperaceae), a Costal and Amazonian Native Species of Ecuador.

Authors:  Gianluca Gilardoni; Yadira Matute; Jorge Ramírez
Journal:  Plants (Basel)       Date:  2020-06-24

7.  Concise Synthesis of Linderaspirone A and Bi-linderone.

Authors:  Fenfen Xiao; Wu Liu; Yunxia Wang; Qing Zhang; Xiang Li; Xiangdong Hu
Journal:  Asian J Org Chem       Date:  2013-01-11       Impact factor: 3.319
  7 in total

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