| Literature DB >> 15174848 |
David M Hodgson1, Christopher D Bray, Nicholas D Kindon.
Abstract
A new reactivity mode of lithium amides with epoxides leads to hindered enamines. The reaction of some of these enamines with unactivated primary and secondary alkyl halides is described, which expands the range of electrophiles that one can use in the synthesis of mono-alkylated aldehydes.Entities:
Year: 2004 PMID： 15174848 DOI： 10.1021/ja031770o
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419