Literature DB >> 15173625

Assaying cytochrome C translocation during apoptosis.

Nigel J Waterhouse1, Rohan Steel, Ruth Kluck, Joseph A Trapani.   

Abstract

Translocation of proteins from the mitochondrial intermembrane space to the cytoplasm is a critical event during apoptosis. There are several methods for assaying this event cited in the literature. In this chapter, we highlight separation of cytosolic and mitochondrial fractions of cultured cells using digitonin as the method for measuring cytochrome c release that, in our hands has been the simplest and most reproducible.

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Year:  2004        PMID： 15173625     DOI： 10.1385/1-59259-816-1:307

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  17 in total

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2.  Proximal events in 7,12-dimethylbenz[a]anthracene-induced, stromal cell-dependent bone marrow B cell apoptosis: stromal cell-B cell communication and apoptosis signaling.

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3.  c-FLIP protects T lymphocytes from apoptosis in the intrinsic pathway.

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Journal:  J Immunol       Date:  2015-02-27       Impact factor: 5.422

4.  The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

Authors:  Mark F van Delft; Andrew H Wei; Kylie D Mason; Cassandra J Vandenberg; Lin Chen; Peter E Czabotar; Simon N Willis; Clare L Scott; Catherine L Day; Suzanne Cory; Jerry M Adams; Andrew W Roberts; David C S Huang
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5.  From the Cover: Tributyltin Alters the Bone Marrow Microenvironment and Suppresses B Cell Development.

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Journal:  Toxicol Sci       Date:  2017-07-01       Impact factor: 4.849

6.  Francisella tularensis Modulates a Distinct Subset of Regulatory Factors and Sustains Mitochondrial Integrity to Impair Human Neutrophil Apoptosis.

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7.  Reovirus infection or ectopic expression of outer capsid protein micro1 induces apoptosis independently of the cellular proapoptotic proteins Bax and Bak.

Authors:  Meagan L Wisniewski; Brenda G Werner; Louis G Hom; Lynne J Anguish; Caroline M Coffey; John S L Parker
Journal:  J Virol       Date:  2010-10-27       Impact factor: 5.103

8.  Neisseria gonorrhoeae-mediated inhibition of apoptotic signalling in polymorphonuclear leukocytes.

Authors:  Adrienne Chen; H Steven Seifert
Journal:  Infect Immun       Date:  2011-08-15       Impact factor: 3.441

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Authors:  Joshua Jabaut; Jennifer L Ather; Alexandra Taracanova; Matthew E Poynter; Karina Ckless
Journal:  Free Radic Biol Med       Date:  2013-01-29       Impact factor: 7.376

10.  Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.

Authors:  Mark D McKenzie; Emma Jamieson; Elisa S Jansen; Clare L Scott; David C S Huang; Philippe Bouillet; Janette Allison; Thomas W H Kay; Andreas Strasser; Helen E Thomas
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