Literature DB >> 15172945

Non-adherence to antipsychotic medication regimens: associations with resource use and costs.

Martin Knapp1, Derek King, Klaus Pugner, Pablo Lapuerta.   

Abstract

BACKGROUND: Several factors are thought to influence resource use and costs in treating schizophrenia. AIMS: To assess the relative impact of non-adherence and other factors associated with resource use and costs incurred by people with schizophrenia.
METHOD: Secondary analyses were made of data from a 1994 national survey of psychiatric morbidity among adults living in institutions in the UK. Factors potentially relating to resource use and costs were examined using two-part models.
RESULTS: Patients who failed to adhere to their medication regimen were over one-and-a-half times as likely as patients who did adhere to it to report use of in-patient services. Non-adherence is one of the most significant factors in increasing external service costs, by a factor of almost 3. Non-adherence predicted an excess annual cost per patient of approximately 2500 British pounds for in-patient services and over 5000 British pounds for total service use.
CONCLUSIONS: Resource use and costs are influenced by various factors. Medication non-adherence consistently exhibits an association with higher costs. Further important factors are patient needs and the ability of the system to address them.

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Year:  2004        PMID: 15172945     DOI: 10.1192/bjp.184.6.509

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN: 0007-1250            Impact factor:   9.319


  54 in total

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4.  Does Non-Adherence Increase Treatment Costs in Schizophrenia?

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8.  Effectiveness, Adverse Effects and Drug Compliance of Long-Acting Injectable Risperidone in Children and Adolescents.

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9.  A Medicaid and commercial insured claims-based study to estimate improved antipsychotic medication adherence among patients with schizophrenia.

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10.  Psychoeducation Improves Compliance and Outcome in Schizophrenia Without an Increase of Adverse Side Effects: A 7-Year Follow-up of the Munich PIP-Study.

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