Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 CLC-K channels: if the drug fits, use it.

Literature DB >> 15170474

CLC-K channels: if the drug fits, use it.

Peying Fong¹.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2004 PMID： 15170474 PMCID： PMC1299078 DOI： 10.1038/sj.embor.7400168

Source DB: PubMed Journal: EMBO Rep ISSN： 1469-221X Impact factor: 8.807

× No keyword cloud information.

12 in total

1. X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.

Authors: Raimund Dutzler; Ernest B Campbell; Martine Cadene; Brian T Chait; Roderick MacKinnon
Journal: Nature Date: 2002-01-17 Impact factor: 49.962

Review 2. Molecular structure and physiological function of chloride channels.

Authors: Thomas J Jentsch; Valentin Stein; Frank Weinreich; Anselm A Zdebik
Journal: Physiol Rev Date: 2002-04 Impact factor: 37.312

3. Mutation of BSND causes Bartter syndrome with sensorineural deafness and kidney failure.

Authors: R Birkenhäger; E Otto; M J Schürmann; M Vollmer; E M Ruf; I Maier-Lutz; F Beekmann; A Fekete; H Omran; D Feldmann; D V Milford; N Jeck; M Konrad; D Landau; N V Knoers; C Antignac; R Sudbrak; A Kispert; F Hildebrandt
Journal: Nat Genet Date: 2001-11 Impact factor: 38.330

4. Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion.

Authors: R Estévez; T Boettger; V Stein; R Birkenhäger; E Otto; F Hildebrandt; T J Jentsch
Journal: Nature Date: 2001-11-29 Impact factor: 49.962

5. Intrarenal and cellular localization of CLC-K2 protein in the mouse kidney.

Authors: Katsuki Kobayashi; Shinichi Uchida; Shuki Mizutani; Sei Sasaki; Fumiaki Marumo
Journal: J Am Soc Nephrol Date: 2001-07 Impact factor: 10.121

6. Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers.

Authors: Antonella Liantonio; Michael Pusch; Alessandra Picollo; Patrizia Guida; Annamaria De Luca; Sabata Pierno; Giuseppe Fracchiolla; Fulvio Loiodice; Paolo Tortorella; Diana Conte Camerino
Journal: J Am Soc Nephrol Date: 2004-01 Impact factor: 10.121

7. Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.

Authors: Y Matsumura; S Uchida; Y Kondo; H Miyazaki; S B Ko; A Hayama; T Morimoto; W Liu; M Arisawa; S Sasaki; F Marumo
Journal: Nat Genet Date: 1999-01 Impact factor: 38.330

8. Molecular determinants of differential pore blocking of kidney CLC-K chloride channels.

Authors: Alessandra Picollo; Antonella Liantonio; Maria Paola Didonna; Laura Elia; Diana Conte Camerino; Michael Pusch
Journal: EMBO Rep Date: 2004-05-28 Impact factor: 8.807

9. Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid.

Authors: Antonella Liantonio; Alessio Accardi; Giuseppe Carbonara; Giuseppe Fracchiolla; Fulvio Loiodice; Paolo Tortorella; Sonia Traverso; Patrizia Guida; Sabata Pierno; Annamaria De Luca; Diana Conte Camerino; Michael Pusch
Journal: Mol Pharmacol Date: 2002-08 Impact factor: 4.436

10. Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1.

Authors: Raúl Estévez; Björn C Schroeder; Alessio Accardi; Thomas J Jentsch; Michael Pusch
Journal: Neuron Date: 2003-04-10 Impact factor: 17.173

8 in total

1. Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels.

Authors: G Zifarelli; A Liantonio; A Gradogna; A Picollo; G Gramegna; M De Bellis; A R Murgia; E Babini; D Conte Camerino; M Pusch
Journal: Br J Pharmacol Date: 2010-08 Impact factor: 8.739

Review 2. Novel diuretic targets.

Authors: Jerod S Denton; Alan C Pao; Merritt Maduke
Journal: Am J Physiol Renal Physiol Date: 2013-07-17

3. Molecular switch for CLC-K Cl- channel block/activation: optimal pharmacophoric requirements towards high-affinity ligands.

Authors: Antonella Liantonio; Alessandra Picollo; Giuseppe Carbonara; Giuseppe Fracchiolla; Paolo Tortorella; Fulvio Loiodice; Antonio Laghezza; Elena Babini; Giovanni Zifarelli; Michael Pusch; Diana Conte Camerino
Journal: Proc Natl Acad Sci U S A Date: 2008-01-23 Impact factor: 11.205