| Literature DB >> 15168863 |
Igor A Parshikov1, Bruhaspathy Miriyala, Mitchell A Avery, John S Williamson.
Abstract
The microbial hydroxylation of 10-deoxoartemisinin was investigated with the aim of obtaining preparative yields of hydroxy derivatives. During 14 d at 28 degrees C and pH 6.5 Aspergillus niger transformed 10-deoxoartemisinin (500 mg l(-1)) to 15-hydroxy-10-deoxoartemisinin (26%) and 7beta-hydroxy-10-deoxoartemisinin (69%).Entities:
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Year: 2004 PMID： 15168863 DOI： 10.1023/b:bile.0000021965.55420.e9
Source DB: PubMed Journal: Biotechnol Lett ISSN： 0141-5492 Impact factor: 2.461