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Literature DB >> 15168195

HIV-1 assembly and maturation.

Abstract

HIV-1 particles have been studied by structural and chemical approaches, however, the processes of assembly, budding and maturation are just beginning to be characterized, and molecular details of these processes remain poorly defined. This brief review summarizes some recent findings on the final steps of the HIV-1 life cycle and touches upon some unanswered questions, particularly regarding the processes involved in virus maturation and infectivity.

Entities: Gene Species

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Year: 2004 PMID： 15168195 DOI： 10.1007/s00705-003-0281-8

Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574

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Cited

16 in total

1. Maturation of papillomavirus capsids.

Authors: Christopher B Buck; Cynthia D Thompson; Yuk-Ying S Pang; Douglas R Lowy; John T Schiller
Journal: J Virol Date: 2005-03 Impact factor: 5.103

2. Molecular factors required for human immunodeficiency virus type I infectivity.

Authors: A G Bukrinskaya; G K Vorkunova; M E Burshteĭn; T V Gorodnicheva; M Stevenson
Journal: Dokl Biol Sci Date: 2005 Jul-Aug

3. The matrix protein of human immunodeficiency virus is cleaved and packed into virion cores.

Authors: A G Bukrinskaya; G K Vorkunova; M E Burshtein; M Stevenson
Journal: Dokl Biol Sci Date: 2006 May-Jun

4. Correct capsid assembly mediated by a conserved YXXLGL motif in prototype foamy virus Gag is essential for infectivity and reverse transcription of the viral genome.

Authors: Ingrid Mannigel; Annett Stange; Hanswalter Zentgraf; Dirk Lindemann
Journal: J Virol Date: 2007-01-17 Impact factor: 5.103

HIV-1 assembly and maturation.

1. Maturation of papillomavirus capsids.

2. Molecular factors required for human immunodeficiency virus type I infectivity.

3. The matrix protein of human immunodeficiency virus is cleaved and packed into virion cores.

4. Correct capsid assembly mediated by a conserved YXXLGL motif in prototype foamy virus Gag is essential for infectivity and reverse transcription of the viral genome.

5. Characterization of replication defects induced by mutations in the basic domain and C-terminus of HIV-1 matrix.

6. Mechanisms of receptor/coreceptor-mediated entry of enveloped viruses.

7. Inhibition of reverse transcriptase activity increases stability of the HIV-1 core.

8. Stoichiometry of envelope glycoprotein trimers in the entry of human immunodeficiency virus type 1.

Review 9. Co-receptor signaling in the pathogenesis of neuroHIV.

10. The relationship between HIV-1 genome RNA dimerization, virion maturation and infectivity.