Literature DB >> 15168043

Surgical management of entero and colocutaneous fistulae in Crohn's disease: 17 year's experience.

Lisa S Poritz1, G Alessandra Gagliano, Robin S McLeod, Helen MacRae, Zane Cohen.   

Abstract

BACKGROUND AND AIMS: Fistulous disease is common in Crohn's disease, and entero- and colocutaneous fistulae are particularly debilitating and difficult to manage. We present the results of surgical management of these fistulas. PATIENTS AND METHODS: Retrospective chart review of all 51 patients with Crohn's disease (56 surgical procedures) undergoing surgery for cutaneous fistulae between 1983 and 2000.
RESULTS: Previous surgery for Crohn's disease had been carried out in 43 patients (84%). The fistula site was enterocutaneous in 36 patients (64%), colocutaneous in 12 (21%), and anastomotic in 8 (14%); 9 patients (16%) also had associated enteroenteric fistulas. The onset of the fistula followed abscess drainage in 15 (27%) and occurred at the site of recurrent disease in 41 (73%). Forty patients (71%) initially underwent conservative management prior to surgery; 16 (28%) underwent surgery directly. Surgical procedures were: 25 ileocolic resections, 8 stoma revisions with resection, 8 small bowel resections 7 subtotal colectomies, 4 partial colectomies, 3 proctocolectomies, and one fistula tract excision. Mean total length of stay was 18 days (postoperative 10.7 days). Six (11%) patients had eight postoperative complications. Mean follow-up was 48.6 months (range 3-187). Recurrence as defined by either clinical examination or reoperation was documented in nine fistulas (16%), with a mean time to recurrence of 27 months.
CONCLUSION: Entero-and colocutaneous fistulae usually occur from a site of active disease. Surgical management with bowel resection, including the fistula, is the preferred method of treatment. Morbidity has been low and recurrence rate lower than expected. Copyright 2004 Springer-Verlag

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Year:  2004        PMID: 15168043     DOI: 10.1007/s00384-004-0580-x

Source DB:  PubMed          Journal:  Int J Colorectal Dis        ISSN: 0179-1958            Impact factor:   2.571


  17 in total

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Review 3.  Review article: the efficacy of infliximab in Crohn's disease--healing of fistulae.

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  12 in total

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Journal:  World J Gastroenterol       Date:  2008-05-07       Impact factor: 5.742

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6.  Early experience with single-site laparoscopic surgery for complicated ileocolic Crohn's disease at a tertiary-referral center.

Authors:  David B Stewart; Evangelos Messaris
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7.  Can Enteric Fistulae in Patients with Crohn's Disease Occur in Isolation: Findings from 500 Consecutive Operative Cases.

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Authors:  Kathryn L Galie; Charles B Whitlow
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