| Literature DB >> 15167352 |
Roland A Ammann1, Andrea Duppenthaler, Juergen Bux, Christoph Aebi.
Abstract
: Chronic neutropenia is common in children with cartilage-hair hypoplasia (CHH). The authors describe a 6-year-old with severe CHH, moderate neutropenia associated with serum IgG antibodies directed against Fcgamma-RIIIb (NA1/2), and frequent bacterial infections. In this patient, long-term administration of granulocyte colony-stimulating factor increased peripheral neutrophil counts and prevented recurrent hospitalizations for bacterial lower respiratory tract infections.Entities:
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Year: 2004 PMID: 15167352 DOI: 10.1097/00043426-200406000-00009
Source DB: PubMed Journal: J Pediatr Hematol Oncol ISSN: 1077-4114 Impact factor: 1.289