Literature DB >> 15167127

Does low dose internal radiation increase lifespan?

Ray D Lloyd1, Glenn N Taylor, Scott C Miller.   

Abstract

No significant differences in lifespan could be established between control dogs and dogs given 241Am, 228Th, 90Sr, 228Ra, 226Ra or monomeric 239Pu at low dosage levels that induced less than 10% skeletal malignancies (low dose animals) in the Utah beagle colony when all dogs surviving at least 1 y were included in the analysis and dogs given individual radionuclides were considered separately or together. Censoring or exclusion of dogs from these groups that were diagnosed with skeletal malignancies or that died in a gran mal epileptic seizure made no important difference to these results. Therefore, an enhanced lifespan of low dose dogs as compared with controls could not be established. It is concluded that low doses from internal (mainly skeletal) deposits of these radionuclides probably do not benefit the survival of individuals so exposed.

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Year:  2004        PMID: 15167127     DOI: 10.1097/00004032-200406000-00009

Source DB:  PubMed          Journal:  Health Phys        ISSN: 0017-9078            Impact factor:   1.316


  1 in total

1.  Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs: effects of aging and long-term aldosterone infusion.

Authors:  Girma Asemu; Kelly A O'Connell; James W Cox; Erinne R Dabkowski; Wenhong Xu; Rogerio F Ribeiro; Kadambari C Shekar; Peter A Hecker; Sharad Rastogi; Hani N Sabbah; Charles L Hoppel; William C Stanley
Journal:  Am J Physiol Heart Circ Physiol       Date:  2012-12-15       Impact factor: 4.733

  1 in total

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