Literature DB >> 15166539

Higher viral load may explain the dominance of CRF02_AG in the molecular epidemiology of HIV in Ghana.

Lucia Fischetti1, Ohene Opare-Sem, Daniel Candotti, Helen Lee, Jean-Pierre Allain.   

Abstract

Phylogenetic analysis of Ghanaian plasma samples from 84 asymptomatic candidate blood donors and 150 AIDS patients revealed a 63% prevalence of HIV-1 CRF02_AG. HIV-1 viral load in both populations was quantified using real-time reverse transcriptase-polymerase chain reaction. In asymptomatic candidate blood donors infected with CRF02_AG, the viral load was significantly higher than in donors infected with other HIV-1 molecular forms. A higher viral load of CRF02-AG is compatible with higher infectivity and prevalence.

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Year:  2004        PMID： 15166539     DOI： 10.1097/00002030-200405210-00017

Source DB:  PubMed          Journal:  AIDS        ISSN： 0269-9370            Impact factor:   4.177


  10 in total

1.  Cognitive Function Among Antiretroviral Treatment-Naive Individuals Infected With Human Immunodeficiency Virus Type 1 Subtype G Versus CRF02_AG in Nigeria.

Authors:  Jibreel Jumare; Nicaise Ndembi; Samer S El-Kamary; Laurence Magder; Laura Hungerford; Tricia Burdo; Lindsay M Eyzaguirre; Patrick Dakum; Anya Umlauf; Mariana Cherner; Alash'le Abimiku; Man Charurat; William A Blattner; Walter Royal
Journal:  Clin Infect Dis       Date:  2018-04-17       Impact factor: 9.079

2.  Molecular epidemiology of HIV type 1 CRF02_AG in Cameroon and African patients living in Italy.

Authors:  Nazle Mendonca Collaço Véras; Maria Mercedes Santoro; Rebecca R Gray; Andrew J Tatem; Alessandra Lo Presti; Flaminia Olearo; Giulia Cappelli; Vittorio Colizzi; Desiré Takou; Judith Torimiro; Gianluca Russo; Annapaola Callegaro; Romina Salpini; Roberta D'Arrigo; Carlo-Federico Perno; Maureen M Goodenow; Massimo Ciccozzi; Marco Salemi
Journal:  AIDS Res Hum Retroviruses       Date:  2011-05-06       Impact factor: 2.205

3.  Multiple CRF01_AE/CRF07_BC Recombinants Enhanced the HIV-1 Epidemic Complexity Among MSM in Shenyang City, Northeast China.

Authors:  Shan He; Wei Song; Gang Guo; Qiang Li; Minghui An; Bin Zhao; Yang Gao; Wen Tian; Lin Wang; Hong Shang; Xiaoxu Han
Journal:  Front Microbiol       Date:  2022-05-12       Impact factor: 6.064

4.  The evolution of HIV-1 group M genetic variability in Southern Cameroon is characterized by several emerging recombinant forms of CRF02_AG and viruses with drug resistance mutations.

Authors:  Lucy Agyingi; Luzia M Mayr; Thompson Kinge; George Enow Orock; Johnson Ngai; Bladine Asaah; Mbida Mpoame; Indira Hewlett; Phillipe Nyambi
Journal:  J Med Virol       Date:  2013-11-19       Impact factor: 2.327

5.  Identification of new, emerging HIV-1 unique recombinant forms and drug resistant viruses circulating in Cameroon.

Authors:  Viswanath Ragupathy; Jiangqin Zhao; Owen Wood; Shixing Tang; Sherwin Lee; Phillipe Nyambi; Indira Hewlett
Journal:  Virol J       Date:  2011-04-23       Impact factor: 4.099

6.  In Silico and In Vitro Comparison of HIV-1 Subtypes B and CRF02_AG Integrases Susceptibility to Integrase Strand Transfer Inhibitors.

Authors:  Xiaoju Ni; Safwat Abdel-Azeim; Elodie Laine; Rohit Arora; Osamuede Osemwota; Anne-Geneviève Marcelin; Vincent Calvez; Jean-François Mouscadet; Luba Tchertanov
Journal:  Adv Virol       Date:  2012-07-05

7.  The predominance of Human Immunodeficiency Virus type 1 (HIV-1) circulating recombinant form 02 (CRF02_AG) in West Central Africa may be related to its replicative fitness.

Authors:  Harr F Njai; Youssef Gali; Guido Vanham; Claude Clybergh; Wim Jennes; Nicole Vidal; Christelle Butel; Eitel Mpoudi-Ngolle; Martine Peeters; Kevin K Ariën
Journal:  Retrovirology       Date:  2006-07-03       Impact factor: 4.602

8.  Transmitted drug resistance mutations and subtype diversity amongst HIV-1 sero-positive voluntary blood donors in Accra, Ghana.

Authors:  Billal Musah Obeng; Evelyn Yayra Bonney; Lucy Asamoah-Akuoko; Nicholas Israel Nii-Trebi; Gifty Mawuli; Christopher Zaab-Yen Abana; Kwamena William Coleman Sagoe
Journal:  Virol J       Date:  2020-07-24       Impact factor: 4.099

9.  Molecular epidemiology of HIV-1 in Oryol Oblast, Russia.

Authors:  Ksenia R Safina; Yulia Sidorina; Natalya Efendieva; Elena Belonosova; Darya Saleeva; Alina Kirichenko; Dmitry Kireev; Vadim Pokrovsky; Georgii A Bazykin
Journal:  Virus Evol       Date:  2022-06-01

10.  Recombinant interferon-γ lentivirus co-infection inhibits adenovirus replication ex vivo.

Authors:  Ling Zhang; Sen Yin; Wanlong Tan; Dong Xiao; Yunceng Weng; Wenjing Wang; Tingting Li; Junwen Shi; Lifang Shuai; Hongwei Li; Jianhua Zhou; Jean-Pierre Allain; Chengyao Li
Journal:  PLoS One       Date:  2012-08-16       Impact factor: 3.240
  10 in total

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