Literature DB >> 1516611

Inhibition by basic drugs of digoxin secretion into human bile.

A Hedman1.   

Abstract

Bile samples from previous interaction studies in man were re-analysed by a combined HPLC/radioimmunoassay method. Quinidine, quinine and verapamil but not probenecid or spironolactone were found to inhibit the biliary secretion of unchanged digoxin.

Entities:  

Mesh：

Substances：

Year:  1992        PMID： 1516611     DOI： 10.1007/bf00280136

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  24 in total

1.  The absorption of orally administered (12 - 3 H)digoxin in man.

Authors:  B Beermann; K Hellström; A Rosén
Journal:  Clin Sci       Date:  1972-10       Impact factor: 6.124

2.  Tritiated digoxin. XIV. Enterohepatic circulation, absorption, and excretion studies in human volunteers.

Authors:  J E Doherty; W J Flanigan; M L Murphy; R T Bulloch; G L Dalrymple; O W Beard; W H Perkins
Journal:  Circulation       Date:  1970-11       Impact factor: 29.690

3.  Quinidine reduces biliary clearance of digoxin in man.

Authors:  B Angelin; A Arvidsson; R Dahlqvist; A Hedman; K Schenck-Gustafsson
Journal:  Eur J Clin Invest       Date:  1987-06       Impact factor: 4.686

4.  Digoxin-interactions in man: spironolactone reduces renal but not biliary digoxin clearance.

Authors:  A Hedman; B Angelin; A Arvidsson; R Dahlqvist
Journal:  Eur J Clin Pharmacol       Date:  1992       Impact factor: 2.953

5.  No effect of probenecid on the renal and biliary clearances of digoxin in man.

Authors:  A Hedman; B Angelin; A Arvidsson; R Dahlqvist
Journal:  Br J Clin Pharmacol       Date:  1991-07       Impact factor: 4.335

6.  Digoxin biotransformation.

Authors:  M H Gault; L L Longerich; J C Loo; P T Ko; A Fine; S C Vasdev; M A Dawe
Journal:  Clin Pharmacol Ther       Date:  1984-01       Impact factor: 6.875

7.  Pharmacokinetics of digoxin in patients subjected to the quinidine-digoxin interaction.

Authors:  K Schenck-Gustafsson; R Dahlqvist
Journal:  Br J Clin Pharmacol       Date:  1981-02       Impact factor: 4.335

8.  Digoxin quinidine interaction: a pharmacokinetic study in the isolated perfused rat liver.

Authors:  J Ben-Itzhak; H M Bassan; R Shor; A Lanir
Journal:  Life Sci       Date:  1985-08-05       Impact factor: 5.037

9.  Effects of basic drugs on the hepatic transport of cardiac glycosides in rats.

Authors:  K Okudaira; Y Sawada; Y Sugiyama; T Iga; M Hanano
Journal:  Biochem Pharmacol       Date:  1988-08-01       Impact factor: 5.858

10.  Excretion of digoxin and its metabolites in urine after a single oral dose in healthy subjects.

Authors:  J O Magnusson; B Bergdahl; C Bogentoft; U E Jonsson; L Tekenbergs
Journal:  Biopharm Drug Dispos       Date:  1982 Jul-Sep       Impact factor: 1.627
View more
  2 in total

Review 1.  Calcium antagonists. Drug interactions of clinical significance.

Authors:  T Rosenthal; D Ezra
Journal:  Drug Saf       Date:  1995-09       Impact factor: 5.606

Review 2.  Cardiac glycosides. Drug interactions of clinical significance.

Authors:  B Magnani; P L Malini
Journal:  Drug Saf       Date:  1995-02       Impact factor: 5.606
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.