Literature DB >> 15165165

A new 3,4-seco-lupane derivative from Lasianthus gardneri.

Sabrina Dallavalle1, Lalith Jayasinghe, B M M Kumarihamy, Lucio Merlini, Loana Musso, Leonardo Scaglioni.   

Abstract

A new seco-ring A lupane triterpene derivative (1), along with lupenone, lupeol, beta-sitosterol, ursolic acid, and stigmasterol 3-O-beta-d-glucoside, were isolated from a methanol extract of mature stems of Lasianthus gardneri, a shrub from the family Rubiaceae growing in Sri Lanka. The structure and stereochemistry of the new compound were determined using a combination of (13)C and (1)H homo- and heteronuclear 2D NMR experiments and from mass spectral data. The structure of 1 was confirmed by partial synthesis from lupeol.

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Year:  2004        PMID: 15165165     DOI: 10.1021/np030374g

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  3 in total

1.  Neuroblastoma SH-SY5Y cytotoxicity, anti-amyloidogenic activity and cyclooxygenase inhibition of Lasianthus trichophlebus (Rubiaceae).

Authors:  Mario A Tan; Mark Wilson D Lagamayo; Grecebio Jonathan D Alejandro; Seong Soo A An
Journal:  3 Biotech       Date:  2020-03-03       Impact factor: 2.406

2.  Lasianosides F-I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of Lasianthus verticillatus (Lour.) Merr.

Authors:  Gadah Abdulaziz Al-Hamoud; Raha Saud Orfali; Yoshio Takeda; Sachiko Sugimoto; Yoshi Yamano; Nawal M Al Musayeib; Omer Ibrahim Fantoukh; Musarat Amina; Hideaki Otsuka; Katsuyoshi Matsunami
Journal:  Molecules       Date:  2020-06-17       Impact factor: 4.411

3.  Lasianosides A-E: New Iridoid Glucosides from the Leaves of Lasianthus verticillatus (Lour.) Merr. and Their Antioxidant Activity.

Authors:  Gadah Abdulaziz Al-Hamoud; Raha Saud Orfali; Shagufta Perveen; Kenta Mizuno; Yoshio Takeda; Tatsuo Nehira; Kazuma Masuda; Sachiko Sugimoto; Yoshi Yamano; Hideaki Otsuka; Katsuyoshi Matsunami
Journal:  Molecules       Date:  2019-11-05       Impact factor: 4.411

  3 in total

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