Literature DB >> 15164075

Organizational challenges in clinical genomic research.

Jill S Altshuler1, David Altshuler.   

Abstract

Genome sequence data are enabling clinical genomic investigation, in which the characteristics of human patients are explored using comprehensive inventories of biomolecules. Successful investigators must navigate rapid technological change, collect and analyse large volumes of data, and engage systems of clinical care. Such projects will increasingly rely on fully integrated multidisciplinary teams, demanding new organizational models in academic biomedical research.

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Year:  2004        PMID: 15164075     DOI: 10.1038/nature02629

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  4 in total

Review 1.  Complex phenotypes and complex genetics: an introduction to genetic studies of complex traits.

Authors:  John W Belmont; Suzanne M Leal
Journal:  Curr Atheroscler Rep       Date:  2005-05       Impact factor: 5.113

Review 2.  Genetic epidemiology of diabetes.

Authors:  M Alan Permutt; Jonathon Wasson; Nancy Cox
Journal:  J Clin Invest       Date:  2005-06       Impact factor: 14.808

3.  Establish good genomic practice to guide medicine forward.

Authors:  Richard W Barker; David A Brindley; Anna Schuh
Journal:  Nat Med       Date:  2013-05       Impact factor: 53.440

Review 4.  Partnering in oncogenetic research--the INHERIT BRCAs experience: opportunities and challenges.

Authors:  Denise Avard; Peter Bridge; Lucie M Bucci; Jocelyne Chiquette; Michel Dorval; Francine Durocher; Doug Easton; Béatrice Godard; David Goldgar; Bartha Maria Knoppers; Rachel Laframboise; Bernard Lespérance; Marie Plante; Sean V Tavtigian; Hélène Vézina; Brenda Wilson; Jacques Simard
Journal:  Fam Cancer       Date:  2006       Impact factor: 2.375

  4 in total

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