Literature DB >> 15163175

A medicinal chemistry perspective on artemisinin and related endoperoxides.

Paul M O'Neill1, Gary H Posner.   

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Year:  2004        PMID: 15163175     DOI: 10.1021/jm030571c

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  97 in total

1.  Reaction of artemisinin with haemoglobin: implications for antimalarial activity.

Authors:  Rangiah Kannan; Krishan Kumar; Dinkar Sahal; Shrikant Kukreti; Virander S Chauhan
Journal:  Biochem J       Date:  2005-01-15       Impact factor: 3.857

2.  Thiazole, oxadiazole, and carboxamide derivatives of artemisinin are highly selective and potent inhibitors of Toxoplasma gondii.

Authors:  Christopher P Hencken; Lorraine Jones-Brando; Claudia Bordón; Remo Stohler; Bryan T Mott; Robert Yolken; Gary H Posner; Lauren E Woodard
Journal:  J Med Chem       Date:  2010-05-13       Impact factor: 7.446

3.  The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials.

Authors:  Amy E Mercer; Ian M Copple; James L Maggs; Paul M O'Neill; B Kevin Park
Journal:  J Biol Chem       Date:  2010-11-08       Impact factor: 5.157

4.  The antimalarial drug artemisinin alkylates heme in infected mice.

Authors:  Anne Robert; Françoise Benoit-Vical; Catherine Claparols; Bernard Meunier
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-09       Impact factor: 11.205

5.  Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas.

Authors:  Kekeli Ekoue-Kovi; Kimberly Yearick; Daniel P Iwaniuk; Jayakumar K Natarajan; John Alumasa; Angel C de Dios; Paul D Roepe; Christian Wolf
Journal:  Bioorg Med Chem       Date:  2008-11-12       Impact factor: 3.641

6.  Mixed steroidal tetraoxanes induce apoptotic cell death in tumor cells.

Authors:  Zeljko Zizak; Zorica Juranić; Dejan Opsenica; Bogdan A Solaja
Journal:  Invest New Drugs       Date:  2008-11-15       Impact factor: 3.850

Review 7.  Malaria biology and disease pathogenesis: insights for new treatments.

Authors:  Louis H Miller; Hans C Ackerman; Xin-zhuan Su; Thomas E Wellems
Journal:  Nat Med       Date:  2013-02-06       Impact factor: 53.440

8.  Pharmacokinetics of the Antischistosomal Lead Ozonide OZ418 in Uninfected Mice Determined by Liquid Chromatography-Tandem Mass Spectrometry.

Authors:  Anna Leonidova; Mireille Vargas; Jörg Huwyler; Jennifer Keiser
Journal:  Antimicrob Agents Chemother       Date:  2016-11-21       Impact factor: 5.191

Review 9.  Natural products: a continuing source of novel drug leads.

Authors:  Gordon M Cragg; David J Newman
Journal:  Biochim Biophys Acta       Date:  2013-02-18

10.  Selection of a trioxaquine as an antimalarial drug candidate.

Authors:  Frédéric Coslédan; Laurent Fraisse; Alain Pellet; François Guillou; Benjamin Mordmüller; Peter G Kremsner; Alicia Moreno; Dominique Mazier; Jean-Pierre Maffrand; Bernard Meunier
Journal:  Proc Natl Acad Sci U S A       Date:  2008-11-05       Impact factor: 11.205

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