| Literature DB >> 15162214 |
Fei Feng1, Kiyoshi Okuyama, Kenichi Niikura, Takashi Ohta, Reiko Sadamoto, Kenji Monde, Toshitada Noguchi, Shin-Ichiro Nishimura.
Abstract
Two non-natural fluorinated 2-N-acetamidosugar nucleotides, uridine 5'-diphosphate (UDP) 2-acetamido-2,4-dideoxy-4-fluoro-alpha-D-glucopyranose (UDP-4-FGlcNAc) 1 and its galacto isomer (UDP-4-FGalNAc) 2, were enzymatically constructed by treating chemically synthesized fluorinated 2-N-acetamidosugar 1-phosphates as the donor with UDP 2-acetamido-2-deoxy-alpha-D-glucopyranose pyrophosphorylase in the presence of uridine 5'-triphosphate (UTP).Entities:
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Year: 2004 PMID： 15162214 DOI： 10.1039/b402860k
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876