Literature DB >> 15159773

Stereoselective alkylation of an Evans auxiliary derivative within a pressure-driven micro reactor.

Charlotte Wiles1, Paul Watts, Stephen J Haswell, Esteban Pombo-Villar.   

Abstract

A simple technique for the diastereoselective alkylation of a metal stabilised enolate is demonstrated within a pressure-driven micro reactor whereby enhanced diastereoselectivities were obtained compared to batch.

Entities:  

Year:  2004        PMID: 15159773     DOI: 10.1039/b400280f

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  2 in total

1.  Continuous-flow catalytic asymmetric hydrogenations: Reaction optimization using FTIR inline analysis.

Authors:  Magnus Rueping; Teerawut Bootwicha; Erli Sugiono
Journal:  Beilstein J Org Chem       Date:  2012-02-23       Impact factor: 2.883

2.  Chiral auxiliary recycling in continuous flow: automated recovery and reuse of Oppolzer's sultam.

Authors:  R J Sullivan; S G Newman
Journal:  Chem Sci       Date:  2018-01-25       Impact factor: 9.825

  2 in total

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