[Nosocomial sinusitis in patients with a severe craniocerebral trauma: etiology and pathogenesis].

The article presents a brief review of the literature on the problem of nosocomial sinusitis (NS) and the experience with 264 patients with craniocerebral trauma in whom NS etiology and pathogenesis were established basing on the findings of microbiological, morphological and immunological studies. Gram-negative opportunistic microflora appeared to be an underlying cause in etiology of NS. Regional microcirculatory disorders due to a severe craniocerebral trauma as well as suppression of nonspecific resistance and immunity contributed most of all to pathogenesis of the disease. Combination of unfavourable etiological and pathogenetic factors in patients with a craniocerebral trauma led to development of NS.