Literature DB >> 15158982

Scopoletin suppresses pro-inflammatory cytokines and PGE2 from LPS-stimulated cell line, RAW 264.7 cells.

Hyung-Jin Kim1, Seon Il Jang, Young-Jun Kim, Hun-Taeg Chung, Yong-Gab Yun, Tai-Hyun Kang, Ok-Sam Jeong, Youn-Chul Kim.   

Abstract

Scopoletin (1-50 microg/ml) inhibited the release of PGE2, TNF-alpha, IL-1beta and IL-6 and suppressed the expression of COX-2 in a concentration-dependent manner. These results suggest that scopoletin might suppress the production of such pro-inflammatory cytokines and exert inhibitory activity on LPS-induced PGE2 production through the depression of COX-2 expression. Copyright 2004 Elsevier B.V.

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Year:  2004        PMID： 15158982     DOI： 10.1016/j.fitote.2003.12.021

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  19 in total

1.  Isolation and identification of antioxidants from Pedilanthus tithymaloides.

Authors:  Pedro M Abreu; Susan Matthew; Tania González; Lucie Vanickova; David Costa; Ana Gomes; Marcela A Segundo; Eduarda Fernandes
Journal:  J Nat Med       Date:  2007-07-31       Impact factor: 2.343

2.  Expression of Mycobacterium leprae HSP65 in tobacco and its effectiveness as an oral treatment in adjuvant-induced arthritis.

Authors:  César Rodríguez-Narciso; Mayra Pérez-Tapia; Rosa María Rangel-Cano; Celio L Silva; Mariana Meckes-Fisher; Rafael Salgado-Garciglia; Sergio Estrada-Parra; Rodolfo López-Gómez; Iris Estrada-García
Journal:  Transgenic Res       Date:  2010-06-06       Impact factor: 2.788

Review 3.  A review of the anticancer and immunomodulatory effects of Lycium barbarum fruit.

Authors:  Wai-Man Tang; Enoch Chan; Ching-Yee Kwok; Yee-Ki Lee; Jian-Hong Wu; Chun-Wai Wan; Robbie Yat-Kan Chan; Peter Hoi-Fu Yu; Shun-Wan Chan
Journal:  Inflammopharmacology       Date:  2011-12-22       Impact factor: 4.473

4.  Soluplus micelles for improving the oral bioavailability of scopoletin and their hypouricemic effect in vivo.

Authors:  Ying-Chun Zeng; Sha Li; Chang Liu; Tao Gong; Xun Sun; Yao Fu; Zhi-Rong Zhang
Journal:  Acta Pharmacol Sin       Date:  2017-01-23       Impact factor: 6.150

5.  Ghrelin secretion is not reduced by increased fat mass during diet-induced obesity.

Authors:  Xiang Qi; Jason T Reed; Guiyun Wang; Song Han; Ella W Englander; George H Greeley
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2008-05-21       Impact factor: 3.619

6.  Ameliorative Effects of Scopoletin from Crossostephium chinensis against Inflammation Pain and Its Mechanisms in Mice.

Authors:  Tien-Ning Chang; Jeng-Shyan Deng; Yi-Chih Chang; Chao-Ying Lee; Liao Jung-Chun; Min-Min Lee; Wen Huang Peng; Shyh-Shyun Huang; Guan-Jhong Huang
Journal:  Evid Based Complement Alternat Med       Date:  2012-09-06       Impact factor: 2.629

7.  Methanol Extract of Artemisia apiacea Hance Attenuates the Expression of Inflammatory Mediators via NF- κ B Inactivation.

Authors:  Ji Choul Ryu; Sang Mi Park; Min Hwangbo; Sung Hui Byun; Sae Kwang Ku; Young Woo Kim; Sang Chan Kim; Seon Young Jee; Il Je Cho
Journal:  Evid Based Complement Alternat Med       Date:  2013-10-22       Impact factor: 2.629

8.  3D-QSAR and Molecular Docking Studies on the TcPMCA1-Mediated Detoxification of Scopoletin and Coumarin Derivatives.

Authors:  Qiu-Li Hou; Jin-Xiang Luo; Bing-Chuan Zhang; Gao-Fei Jiang; Wei Ding; Yong-Qiang Zhang
Journal:  Int J Mol Sci       Date:  2017-06-27       Impact factor: 5.923

9.  Antibacterial efficacy and effect of Morinda citrifolia L. mixed with irreversible hydrocolloid for dental impressions: A randomized controlled trial.

Authors:  A Shafath Ahmed; P David Charles; R Cholan; M Russia; R Surya; L Jailance
Journal:  J Pharm Bioallied Sci       Date:  2015-08

Review 10.  Artemisia annua, a Traditional Plant Brought to Light.

Authors:  Axelle Septembre-Malaterre; Mahary Lalarizo Rakoto; Claude Marodon; Yosra Bedoui; Jessica Nakab; Elisabeth Simon; Ludovic Hoarau; Stephane Savriama; Dominique Strasberg; Pascale Guiraud; Jimmy Selambarom; Philippe Gasque
Journal:  Int J Mol Sci       Date:  2020-07-15       Impact factor: 5.923
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