Literature DB >> 15158588

Localization of infection-related epitopes on the non-structural protein 3ABC of foot-and-mouth disease virus and the application of tandem epitopes.

Tao Sun1, Ping Lu, Xin Wang.   

Abstract

By means of overlapping peptides expressed in Escherichia coli in combination with Western-blotting, infection specific linear epitopes were identified on the non-structural protein 3ABC of FMDV. The epitopes reacted with sera from pigs or guinea pigs infected with different serotypes of FMDV, but not with sera from normal or vaccinated animals. A protein was constructed by tandem repeat of the epitope covering amino acid residues 141-190 on 3ABC. An ELISA based on the protein with tandem epitopes could be used as a diagnostic antigen for differentiating infected pigs from vaccinated ones.

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Year:  2004        PMID： 15158588     DOI： 10.1016/j.jviromet.2004.02.016

Source DB:  PubMed          Journal:  J Virol Methods        ISSN： 0166-0934            Impact factor:   2.014


  9 in total

Review 1.  An overview on ELISA techniques for FMD.

Authors:  Li-na Ma; Jie Zhang; Hao-tai Chen; Jian-hua Zhou; Yao-zhong Ding; Yong-sheng Liu
Journal:  Virol J       Date:  2011-09-04       Impact factor: 4.099

2.  Pan-Serotype Diagnostic for Foot-and-Mouth Disease Using the Consensus Antigen of Nonstructural Protein 3B.

Authors:  Alyssa K Van Dreumel; Wojtek P Michalski; Leanne M McNabb; Brian J Shiell; Nagendrakumar B Singanallur; Grantley R Peck
Journal:  J Clin Microbiol       Date:  2015-03-18       Impact factor: 5.948

3.  B cell epitopes within VP1 of type O foot-and-mouth disease virus for detection of viral antibodies.

Authors:  Shan-dian Gao; Jun-zheng Du; Hui-yun Chang; Guo-zheng Cong; Jun-Jun Shao; Tong Lin; Shuai Song; Qing-ge Xie
Journal:  Virol Sin       Date:  2010-02-12       Impact factor: 4.327

4.  Serological survey for foot-and-mouth disease virus in wildlife in eastern Africa and estimation of test parameters of a nonstructural protein enzyme-linked immunosorbent assay for buffalo.

Authors:  B M D C Bronsvoort; S Parida; I Handel; S McFarland; L Fleming; P Hamblin; R Kock
Journal:  Clin Vaccine Immunol       Date:  2008-04-02

5.  Adenovirus-mediated RNA interference against foot-and-mouth disease virus infection both in vitro and in vivo.

Authors:  Weizao Chen; Mingqiu Liu; Ye Jiao; Weiyao Yan; Xuefeng Wei; Jiulian Chen; Liang Fei; Yang Liu; Xiaoping Zuo; Fugui Yang; Yonggan Lu; Zhaoxin Zheng
Journal:  J Virol       Date:  2006-04       Impact factor: 5.103

6.  Attenuated Salmonella choleraesuis-mediated RNAi targeted to conserved regions against foot-and-mouth disease virus in guinea pigs and swine.

Authors:  Wei Cong; Hong Jin; Chengda Jiang; Weiyao Yan; Mingqiu Liu; Jiulian Chen; Xiaoping Zuo; Zhaoxin Zheng
Journal:  Vet Res       Date:  2010-01-13       Impact factor: 3.683

7.  Induction of a protective antibody response to FMDV in mice following oral immunization with transgenic Stylosanthes spp. as a feedstuff additive.

Authors:  Dong Mei Wang; Jian Bo Zhu; Ming Peng; Peng Zhou
Journal:  Transgenic Res       Date:  2008-07-24       Impact factor: 2.788

8.  Serological investigation of some important RNA viruses affecting sheep and goats in Giza and Beni-Suef governorates in Egypt.

Authors:  Mohamed Abd El-Fatah Mahmoud; Mohamed Karam Elbayoumy; Doaa Sedky; Sahar Ahmed
Journal:  Vet World       Date:  2017-10-02

9.  Serological Survey of Foot-and-Mouth Disease Virus in Buffaloes (Syncerus caffer) in Zambia.

Authors:  T K W Sikombe; A S Mweene; John Muma; C Kasanga; Y Sinkala; F Banda; M Mulumba; E M Fana; C Mundia; M Simuunza
Journal:  Vet Med Int       Date:  2015-08-05
  9 in total

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