| Literature DB >> 15158199 |
Karina R B Bastos1, Claudio R F Marinho, Renato Barboza, Momtchilo Russo, José M Alvarez, Maria Regina D'Império Lima.
Abstract
The present review illustrates the current knowledge on the autocrine effect of IL-12, and the putative contribution of IL-23, on macrophages and dendritic cells, focusing on cell activation and microbicidal activity. Here, we present convincing evidence that IL-12 is not only a connective element between accessory cells and lymphocytes, but it is also a key molecule for programming the macrophage and dendritic cell functions.Entities:
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Year: 2004 PMID: 15158199 DOI: 10.1016/j.micinf.2004.02.012
Source DB: PubMed Journal: Microbes Infect ISSN: 1286-4579 Impact factor: 2.700