Literature DB >> 15158085

Apoptosis in acute leukemia.

Dezso Schuler1, Béla Szende.   

Abstract

In leukemias and malignant tumors the balance between apoptosis and cell proliferation is dysregulated. This review deals with the apoptosis in acute leukemia. There are several publications about the molecular basis of decreased apoptosis in acute lymphoid leukemia (ALL) and AML. However, there have been contradictory results. Different results are published about the correlation of the spontaneous and induced apoptosis in leukemia with prognosis. The potential causes of these contradictions are discussed.

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Year:  2004        PMID： 15158085     DOI： 10.1016/j.leukres.2003.10.032

Source DB:  PubMed          Journal:  Leuk Res        ISSN： 0145-2126            Impact factor:   3.156


  6 in total

1.  Synthesis and Evaluation of Haloacetyl, α-Bromoacryloyl and Nitrooxyacetyl Benzo[b]furan and Benzo[b]thiophene Derivatives as Potent Antiproliferative Agents Against Leukemia L1210 and K562 Cells.

Authors:  Romeo Romagnoli; Pier Giovanni Baraldi; Maria Dora Carrion; Carlota Lopez Cara; Alberto Casolari; Ernest Hamel; Enrica Fabbri; Roberto Gambari
Journal:  Lett Drug Des Discov       Date:  2010-08-01       Impact factor: 1.150

2.  The effect of apigenin and chemotherapy combination treatments on apoptosis-related genes and proteins in acute leukaemia cell lines.

Authors:  Amani A Mahbub; Christine L Le Maitre; Neil A Cross; Nicola Jordan-Mahy
Journal:  Sci Rep       Date:  2022-05-25       Impact factor: 4.996

3.  Discovery of 8-methoxypyrazino[1,2-a]indole as a New Potent Antiproliferative Agent Against Human Leukemia K562 Cells. A Structure-Activity Relationship Study.

Authors:  Romeo Romagnoli; Pier Giovanni Baraldi; Maria Dora Carrion; Olga Cruz-Lopez; Carlota Lopez Cara; Delia Preti; Mojgan Aghazadeh Tabrizi; Jan Balzarini; Ernest Hamel; Enrica Fabbri; Roberto Gambari
Journal:  Lett Drug Des Discov       Date:  2009-06-01       Impact factor: 1.150

4.  E4BP4 facilitates glucocorticoid-evoked apoptosis of human leukemic CEM cells via upregulation of Bim.

Authors:  Jessica A Beach; Laura J Nary; Yasuko Hirakawa; Eli Holland; Rebeka Hovanessian; Rheem D Medh
Journal:  J Mol Signal       Date:  2011-10-05

5.  Extracellular HMGB1 interacts with RAGE and promotes chemoresistance in acute leukemia cells.

Authors:  Weixin Lai; Xinyu Li; Qian Kong; Han Chen; Yunyao Li; Lu-Hong Xu; Jianpei Fang
Journal:  Cancer Cell Int       Date:  2021-12-21       Impact factor: 5.722

6.  Enhanced levels of the apoptotic BAX/BCL-2 ratio in children with acute lymphoblastic leukemia and high-risk features.

Authors:  Maria Kaparou; Despoina Choumerianou; Chrysoula Perdikogianni; Georgia Martimianaki; Maria Kalmanti; Eftichia Stiakaki
Journal:  Genet Mol Biol       Date:  2013-03-04       Impact factor: 1.771
  6 in total

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