Literature DB >> 15158052

Is whole-culture synchronization biology's 'perpetual-motion machine'?

Stephen Cooper1.   

Abstract

Whole-culture or batch synchronization cannot, in theory, produce a synchronized culture because it violates a fundamental law that proposes that no batch treatment can alter the cell-age order of a culture. In analogy with the history of perpetual-motion machines, it is suggested that the study of these whole-culture 'synchronization' methods might lead to an understanding of general biological principles even though these methods cannot be used to study the normal cell cycle.

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Year:  2004        PMID: 15158052     DOI: 10.1016/j.tibtech.2004.04.009

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  6 in total

1.  Thymidine block does not synchronize L1210 mouse leukaemic cells: implications for cell cycle control, cell cycle analysis and whole-culture synchronization.

Authors:  S Cooper; K Z Chen; S Ravi
Journal:  Cell Prolif       Date:  2008-02       Impact factor: 6.831

2.  Inference of cell cycle-dependent proteolysis by laser scanning cytometry.

Authors:  Abhishek A Chakraborty; William P Tansey
Journal:  Exp Cell Res       Date:  2009-01-27       Impact factor: 3.905

3.  Oscillatory dynamics of cell cycle proteins in single yeast cells analyzed by imaging cytometry.

Authors:  David A Ball; Julie Marchand; Magaly Poulet; William T Baumann; Katherine C Chen; John J Tyson; Jean Peccoud
Journal:  PLoS One       Date:  2011-10-26       Impact factor: 3.240

4.  Comment on and reply to "Analysis of variation of amplitudes in cell cycle gene expression" by Liu, Gaido and Wolfinger: on the analysis of gene expression during the normal, eukaryotic, cell cycle.

Authors:  Stephen Cooper
Journal:  Theor Biol Med Model       Date:  2005-11-18       Impact factor: 2.432

5.  The kinetochore-dependent and -independent formation of the CDC20-MAD2 complex and its functions in HeLa cells.

Authors:  Jianquan Li; Nanmao Dang; Daniel James Wood; Jun-Yong Huang
Journal:  Sci Rep       Date:  2017-01-23       Impact factor: 4.379

6.  Cell cycle synchronisation of Trypanosoma brucei by centrifugal counter-flow elutriation reveals the timing of nuclear and kinetoplast DNA replication.

Authors:  Corinna Benz; Frank Dondelinger; Paul G McKean; Michael D Urbaniak
Journal:  Sci Rep       Date:  2017-12-14       Impact factor: 4.379

  6 in total

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