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Literature DB >> 15155684

Anaplasma phagocytophilum infection induces protracted neutrophil degranulation.

Kyoung-seong Choi¹, Dennis J Grab, J Stephen Dumler.

Abstract

Anaplasma phagocytophilum-infected neutrophil degranulation could exacerbate inflammation. Thus, the degranulation of infected neutrophils was assayed. Infected neutrophils expressed CD11b and CD66b, and supernatants of infected neutrophils showed more proMMP-9 and MMP-9 activity than controls and continued to do so for > or =18 h. Degranulation-related inflammatory tissue injury may account for some clinical manifestations in human granulocytic anaplasmosis.

Entities: Disease Species

Mesh：

Substances：

Year: 2004 PMID： 15155684 PMCID： PMC415649 DOI： 10.1128/IAI.72.6.3680-3683.2004

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

17 in total

Review 1. Neutrophils: molecules, functions and pathophysiological aspects.

Authors: V Witko-Sarsat; P Rieu; B Descamps-Latscha; P Lesavre; L Halbwachs-Mecarelli
Journal: Lab Invest Date: 2000-05 Impact factor: 5.662

Review 2. Neutrophil granules and secretory vesicles in inflammation.

Authors: Mikkel Faurschou; Niels Borregaard
Journal: Microbes Infect Date: 2003-11 Impact factor: 2.700

Review 3. Gelatinase B functions as regulator and effector in leukocyte biology.

Authors: G Opdenakker; P E Van den Steen; B Dubois; I Nelissen; E Van Coillie; S Masure; P Proost; J Van Damme
Journal: J Leukoc Biol Date: 2001-06 Impact factor: 4.962

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Authors: J S Bakken; J S Dumler
Journal: Clin Infect Dis Date: 2000-09-14 Impact factor: 9.079

5. Intracellular infection by the human granulocytic ehrlichiosis agent inhibits human neutrophil apoptosis.

Authors: K Yoshiie; H Y Kim; J Mott; Y Rikihisa
Journal: Infect Immun Date: 2000-03 Impact factor: 3.441

6. Exploitation of interleukin-8-induced neutrophil chemotaxis by the agent of human granulocytic ehrlichiosis.

Authors: M Akkoyunlu; S E Malawista; J Anguita; E Fikrig
Journal: Infect Immun Date: 2001-09 Impact factor: 3.441

7. Cutting edge: infection by the agent of human granulocytic ehrlichiosis prevents the respiratory burst by down-regulating gp91phox.

Authors: R Banerjee; J Anguita; D Roos; E Fikrig
Journal: J Immunol Date: 2000-04-15 Impact factor: 5.422

8. Early induction and late abrogation of respiratory burst in A. phagocytophilum-infected neutrophils.

Authors: Kyoung-Seong Choi; J Stephen Dumler
Journal: Ann N Y Acad Sci Date: 2003-06 Impact factor: 5.691

9. Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models.

Authors: Fons A J van de Loo; Miranda B Bennink; Onno J Arntz; Ruben L Smeets; Erik Lubberts; Leo A B Joosten; Peter L E M van Lent; Christina J J Coenen-de Roo; Salvatore Cuzzocrea; Brahm H Segal; Steven M Holland; Wim B van den Berg
Journal: Am J Pathol Date: 2003-10 Impact factor: 4.307

10. Diminished adhesion of Anaplasma phagocytophilum-infected neutrophils to endothelial cells is associated with reduced expression of leukocyte surface selectin.

Authors: Kyoung-Seong Choi; Justin Garyu; Jinho Park; J Stephen Dumler
Journal: Infect Immun Date: 2003-08 Impact factor: 3.441

17 in total

1. Anaplasma phagocytophilum delay of neutrophil apoptosis through the p38 mitogen-activated protein kinase signal pathway.

Authors: Kyoung-Seong Choi; Joon Tae Park; J Stephen Dumler
Journal: Infect Immun Date: 2005-12 Impact factor: 3.441

2. Early transcriptional response of human neutrophils to Anaplasma phagocytophilum infection.

Authors: Bindu Sukumaran; Jason A Carlyon; Ji-Lian Cai; Nancy Berliner; Erol Fikrig
Journal: Infect Immun Date: 2005-12 Impact factor: 3.441

3. Chromatin-bound bacterial effector ankyrin A recruits histone deacetylase 1 and modifies host gene expression.

Authors: Kristen E Rennoll-Bankert; Jose C Garcia-Garcia; Sara H Sinclair; J Stephen Dumler
Journal: Cell Microbiol Date: 2015-06-11 Impact factor: 3.715

4. Neutrophils exposed to A. phagocytophilum under shear stress fail to fully activate, polarize, and transmigrate across inflamed endothelium.

Authors: U Y Schaff; K A Trott; S Chase; K Tam; J L Johns; J A Carlyon; D C Genetos; N J Walker; S I Simon; D L Borjesson
Journal: Am J Physiol Cell Physiol Date: 2010-04-14 Impact factor: 4.249

5. Defective phagocytosis in Anaplasma phagocytophilum-infected neutrophils.

Authors: Justin W A Garyu; Kyoung-seong Choi; Dennis J Grab; J Stephen Dumler
Journal: Infect Immun Date: 2005-02 Impact factor: 3.441

6. A morphological and molecular study of Anaplasma phagocytophilum transmission events at the time of Ixodes ricinus tick bite.

Authors: Erik G Granquist; Mona Aleksandersen; Karin Bergström; Stephen J Dumler; Wenche O Torsteinbø; Snorre Stuen
Journal: Acta Vet Scand Date: 2010-06-17 Impact factor: 1.695

7. Anaplasma phagocytophilum-Borrelia burgdorferi coinfection enhances chemokine, cytokine, and matrix metalloprotease expression by human brain microvascular endothelial cells.

Authors: Dennis J Grab; Elvis Nyarko; Nicole C Barat; Olga V Nikolskaia; J Stephen Dumler
Journal: Clin Vaccine Immunol Date: 2007-09-26