Literature DB >> 15155249

Lack of effect of recombinant human growth hormone on the in vitro activities of antiretroviral drugs against human immunodeficiency virus type 1.

Mark A Wainberg1, Bluma G Brenner, Eric Daar, Joseph M Gertner, Clement Olivier, Susan Kenley.   

Abstract

We studied the effects of recombinant human growth hormone (r-hGH) on human immunodeficiency virus type 1 replication by growing both wild-type and drug-resistant variants of virus in the presence of various concentrations of eight different antiretroviral drugs. r-hGH had no significant effect on either viral replication or the 50% inhibitory concentrations of these compounds.

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Year:  2004        PMID： 15155249      PMCID： PMC415577          DOI： 10.1128/AAC.48.6.2337-2340.2004

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  20 in total

1.  Comparison of dose-effect relationships of carcinogens following low-dose chronic exposure and high-dose single injection: an analysis by the median-effect principle.

Authors:  T C Chou
Journal:  Carcinogenesis       Date:  1980-03       Impact factor: 4.944

2.  Effects of recombinant human growth hormone on fat distribution in patients with human immunodeficiency virus-associated wasting.

Authors:  Viva W Tai; Morris Schambelan; Heather Algren; Clara Shayevich; Kathleen Mulligan
Journal:  Clin Infect Dis       Date:  2002-10-23       Impact factor: 9.079

3.  Body composition studies in patients with the acquired immunodeficiency syndrome.

Authors:  D P Kotler; J Wang; R N Pierson
Journal:  Am J Clin Nutr       Date:  1985-12       Impact factor: 7.045

4.  Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone.

Authors:  Laura A Napolitano; Joan C Lo; Michael B Gotway; Kathleen Mulligan; Jason D Barbour; Diane Schmidt; Robert M Grant; Robert A Halvorsen; Morris Schambelan; Joseph M McCune
Journal:  AIDS       Date:  2002-05-24       Impact factor: 4.177

Review 5.  HIV-associated wasting in the era of HAART: a practice-based approach to diagnosis and treatment.

Authors:  C R Steinhart
Journal:  AIDS Read       Date:  2001-11

Review 6.  HIV-associated wasting in the HAART era: guidelines for assessment, diagnosis, and treatment.

Authors:  B Polsky; D Kotler; C Steinhart
Journal:  AIDS Patient Care STDS       Date:  2001-08       Impact factor: 5.078

7.  Protein and energy metabolism with biosynthetic human growth hormone after gastrointestinal surgery.

Authors:  H C Ward; D Halliday; A J Sim
Journal:  Ann Surg       Date:  1987-07       Impact factor: 12.969

8.  Growth hormone stimulates protein synthesis during hypocaloric parenteral nutrition. Role of hormonal-substrate environment.

Authors:  J M Manson; R J Smith; D W Wilmore
Journal:  Ann Surg       Date:  1988-08       Impact factor: 12.969

9.  Genetic divergence of human immunodeficiency virus type 1 Ethiopian clade C reverse transcriptase (RT) and rapid development of resistance against nonnucleoside inhibitors of RT.

Authors:  Hugues Loemba; Bluma Brenner; Michael A Parniak; Shlomo Ma'ayan; Bonnie Spira; Daniela Moisi; Maureen Oliveira; Mervi Detorio; Mark A Wainberg
Journal:  Antimicrob Agents Chemother       Date:  2002-07       Impact factor: 5.191

10.  In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA.

Authors:  M A Wainberg; M D Miller; Y Quan; H Salomon; A S Mulato; P D Lamy; N A Margot; K E Anton; J M Cherrington
Journal:  Antivir Ther       Date:  1999
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