| Literature DB >> 15155247 |
Ruzena Stránská1, Rob Schuurman, David R Scholl, Joseph A Jollick, Carl J Shaw, Caroline Loef, Merjo Polman, Anton M van Loon.
Abstract
A colorimetric yield reduction assay, ELVIRA (enzyme-linked virus inhibitor reporter assay) HSV, was developed to determine the antiviral drug susceptibilities of herpes simplex virus (HSV). It uses an HSV-inducible reporter cell line. This simple and rapid assay has an objective readout, low inoculum size, and good reproducibility. The results correlate well with those of the plaque reduction assay.Mesh:
Substances:
Year: 2004 PMID: 15155247 PMCID: PMC415590 DOI: 10.1128/AAC.48.6.2331-2333.2004
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191