Literature DB >> 1515250

Feasibility of measuring oxygen tension in uterine cervix carcinoma.

E Lartigau1, L Vitu, C Haie-Meder, M F Cosset, M Delapierre, A Gerbaulet, F Eschwege, M Guichard.   

Abstract

Cellular hypoxia is a cause of radioresistance. The oxygen tension (pO2) in normal tissues and in tumours can be measured by polarography. In this feasibility study we have measured the tissue pO2 of 10 patients suffering from uterine cervix carcinoma, using the Eppendorf histograph. The measurements were performed at the time of the brachytherapy after external radiotherapy. The machine was found to be reliable and no adverse effect was noted. The mean pO2 values in tumours were lower than those of normal tissues.

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Year:  1992        PMID: 1515250     DOI: 10.1016/0959-8049(92)90518-7

Source DB:  PubMed          Journal:  Eur J Cancer        ISSN: 0959-8049            Impact factor:   9.162


  2 in total

1.  Correlation of [18F]FMISO autoradiography and pimonidazole [corrected] immunohistochemistry in human head and neck carcinoma xenografts.

Authors:  Esther G C Troost; Peter Laverman; Mariëlle E P Philippens; Jasper Lok; Albert J van der Kogel; Wim J G Oyen; Otto C Boerman; Johannes H A M Kaanders; Johan Bussink
Journal:  Eur J Nucl Med Mol Imaging       Date:  2008-04-18       Impact factor: 9.236

Review 2.  Blood flow and oxygenation status of human tumors. Clinical investigations.

Authors:  H J Feldmann; M Molls; P Vaupel
Journal:  Strahlenther Onkol       Date:  1999-01       Impact factor: 3.621

  2 in total

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