Literature DB >> 15151421

A new general access to either type of Securinega alkaloids: synthesis of securinine and (-)-allonorsecurinine.

Ramon Alibés1, Marta Ballbé, Félix Busqué, Pedro de March, Laia Elias, Marta Figueredo, Josep Font.   

Abstract

The syntheses of securinine and (-)-allonorsecurinine have been achieved starting from easily available alpha-amino acid derivatives and using as key steps a RCM and a Heck reaction for the formation of rings D and C, respectively. [reaction: see text]

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Year:  2004        PMID: 15151421     DOI: 10.1021/ol049455+

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

1.  An Enantioselective Approach to the Securinega Alkaloids: The Total Synthesis of (+)-Norsecurinine and (+)-Allonorsecurinine.

Authors:  Matthew R Medeiros; John L Wood
Journal:  Tetrahedron       Date:  2010-06-26       Impact factor: 2.457

  1 in total

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