Literature DB >> 15151183

The role of the substantia nigra in cognitive activity in cats.

E I Mukhin1, Yu K Mukhina, T N Nabieva.   

Abstract

The role of the substantia nigra in cognitive processes of different levels of complexity was studied using an original method. Neurosurgical or neurochemical exclusion of the substantia nigra in cats led to significant impairment of conditioned reflex activity, generalization and abstraction processes; these recovered with pharmacological treatment directed to the dopaminergic system, with partial recovery after treatment directed to the GABAergic and cholinergic systems. Treatment directed to the serotoninergic system was ineffective.

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Year:  2004        PMID: 15151183     DOI: 10.1023/b:neab.0000012808.55321.25

Source DB:  PubMed          Journal:  Neurosci Behav Physiol        ISSN: 0097-0549


  7 in total

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  2 in total

1.  Lessons learnt from animal models: pathophysiology of neuropathic lysosomal storage disorders.

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2.  The homotopic connectivity of the functional brain: a meta-analytic approach.

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Journal:  Sci Rep       Date:  2019-03-04       Impact factor: 4.379

  2 in total

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