AIMS: Velocity changes in the solar wind, recorded by satellite (IMP8 and Wind) are characterized by a solar cycle dependent approximately 1.3-year component. The presence of any approximately 1.3-year component in human blood pressure (BP) and heart rate (HR) and in mortality from myocardial infarction (MI) is tested and its relative prominence compared to the 1.0-year variation. MATERIALS AND METHODS: Around the clock manual or automatic BP and HR measurements from four subjects recorded over 5 to 35 years and a 29-year record of mortality from MI in Minnesota were analyzed by linear-nonlinear rhythmometry. Point and 95% confidence interval (CI) estimates were obtained for the approximately 1.3-year period and amplitude. The latter is compared with the 1.0-year amplitude for BP and HR records concurrent to the solar data provided by one of us (JDR). RESULTS: An approximately 1.3-year component is resolved nonlinearly for MI, with a period of 1.23 (95% CI: 1.21; 1.26) year. This component was invariably validated with statistical significance for BP and HR by linear rhythmometry. Nonlinearly, the 95% CI for the 1.3-year amplitude did not overlap zero in 11 of the 12 BP and HR series. Given the usually strong synchronizing role of light and temperature, it is surprising that 5 of the 12 cardiovascular series had a numerically larger amplitude of the 1.3-year versus the precise 1.0-year component. The beating of the approximately 1.3-year and 1.0-year components was shown by gliding spectra on actual and simulated data. DISCUSSION AND CONCLUSION: The shortest 5-year record (1998-2003) revealed an approximately 1.3-year component closer to the solar wind speed period characterizing the entire available record (1994-2003) than that for the concurrent 5-year span. Physiological variables may resonate with non-photic environmental cycles that may have entered the genetic code during evolution.
AIMS: Velocity changes in the solar wind, recorded by satellite (IMP8 and Wind) are characterized by a solar cycle dependent approximately 1.3-year component. The presence of any approximately 1.3-year component in human blood pressure (BP) and heart rate (HR) and in mortality from myocardial infarction (MI) is tested and its relative prominence compared to the 1.0-year variation. MATERIALS AND METHODS: Around the clock manual or automatic BP and HR measurements from four subjects recorded over 5 to 35 years and a 29-year record of mortality from MI in Minnesota were analyzed by linear-nonlinear rhythmometry. Point and 95% confidence interval (CI) estimates were obtained for the approximately 1.3-year period and amplitude. The latter is compared with the 1.0-year amplitude for BP and HR records concurrent to the solar data provided by one of us (JDR). RESULTS: An approximately 1.3-year component is resolved nonlinearly for MI, with a period of 1.23 (95% CI: 1.21; 1.26) year. This component was invariably validated with statistical significance for BP and HR by linear rhythmometry. Nonlinearly, the 95% CI for the 1.3-year amplitude did not overlap zero in 11 of the 12 BP and HR series. Given the usually strong synchronizing role of light and temperature, it is surprising that 5 of the 12 cardiovascular series had a numerically larger amplitude of the 1.3-year versus the precise 1.0-year component. The beating of the approximately 1.3-year and 1.0-year components was shown by gliding spectra on actual and simulated data. DISCUSSION AND CONCLUSION: The shortest 5-year record (1998-2003) revealed an approximately 1.3-year component closer to the solar wind speed period characterizing the entire available record (1994-2003) than that for the concurrent 5-year span. Physiological variables may resonate with non-photic environmental cycles that may have entered the genetic code during evolution.
Authors: Franz Halberg; Germaine Cornélissen; Kuniaki Otsuka; Yoshihiko Watanabe; Ram B Singh; Miguel Revilla; Salvador Sanchez de la Peña; Clicerio Gonzalez; Jarmila Siegelova; Pavel Homolka; Jiri Dusek; Michal Zeman; Rk Singh; Dana Johnson; Bohumil Fiser Journal: World Heart J Date: 2008
Authors: G Cornélissen; F Halberg; M Mikulecky; P Florida; P Faraone; T Yamanaka; S Murakami; K Otsuka; E E Bakken Journal: Biomed Pharmacother Date: 2005-10 Impact factor: 6.529
Authors: G Cornélissen; F Halberg; E E Bakken; Z Wang; R Tarquini; F Perfetto; G Laffi; C Maggioni; Y Kumagai; P Homolka; A Havelková; J Dušek; H Svačinová; J Siegelová; B Fišer Journal: Scr Med (Brno) Date: 2007-10
Authors: G Yamanaka; K Otsuka; N Hotta; S Murakami; Y Kubo; O Matsuoka; E Takasugi; T Yamanaka; M Shinagawa; S Nunoda; Y Nishimura; K Shibata; H Saitoh; M Nishinaga; M Ishine; T Wada; K Okumiya; K Matsubayashi; S Yano; S Ishizuka; K Ichihara; G Cornélissen; F Halberg Journal: Biomed Pharmacother Date: 2005-10 Impact factor: 6.529
Authors: S Murakami; G Cornélissen; G Katinas; G Mitsutake; K Otsuka; T Breus; M Gigolashvili; B Fišer; J Pazdírek; H Svaèinová; J Siegelova; F Halberg Journal: Scr Med (Brno) Date: 2005-04-01
Authors: T Yamanaka; G Cornélissen; M Kazuma; N Kazuma; S Murakami; K Otsuka; J Siegelová; J Dušek; M Sosíková; F Halberg Journal: Scr Med (Brno) Date: 2005