Literature DB >> 15150814

Lower-extremity amputations in patients with diabetes: pre- and post-surgical decisions related to successful rehabilitation.

Brian L Davis1, Jennifer Kuznicki, S Solomon Praveen, James J Sferra.   

Abstract

BACKGROUND: Peripheral vascular disease and diabetes account for the majority of lower-extremity amputations in the adult population. Whenever a patient presents to a surgeon regarding a diseased limb, the initial basic decision is to determine whether to attempt limb salvage or proceed with an amputation. Unfortunately, limb salvage is not an option for many of these patients. Once amputation is chosen as a treatment option, the optimal level of amputation has to be determined by the surgeon, who is then faced with selecting the optimal level of amputation compatible with wound healing and subsequent prosthetic fitting.
METHODS: Methods for objectively determining optimal amputation level include vascular evaluations, assessing the level of cellulites or osteomyelitis, or intra-operatively, by looking at the amount of bleeding in skin flaps.
RESULTS: The net outcome is that there is currently no universally accepted method for determining the level of amputation for successful wound healing or for preventing subsequent higher amputations.
CONCLUSIONS: What is generally recognized is that there are disparities in the rates of amputation for type 1 versus type 2 diabetic patients, for different ethnic groups and for patients with multiple co-morbidities. However, with advances in surgical techniques and with modern prosthetics, all categories of patients are benefiting from surgeries in which a longer residual limb can be kept (within surgical constraints related to proper wound healing), and where appropriate biomechanical considerations are taken into account. Copyright 2004 John Wiley & Sons, Ltd.

Entities:  

Mesh:

Year:  2004        PMID: 15150814     DOI: 10.1002/dmrr.445

Source DB:  PubMed          Journal:  Diabetes Metab Res Rev        ISSN: 1520-7552            Impact factor:   4.876


  4 in total

1.  Hyperspectral imaging in wound care: A systematic review.

Authors:  Gennadi Saiko; Phoebe Lombardi; Yunghan Au; Douglas Queen; David Armstrong; Keith Harding
Journal:  Int Wound J       Date:  2020-08-23       Impact factor: 3.315

2.  The use of a dermal substitute to preserve maximal foot length in diabetic foot wounds with tendon and bone exposure following urgent surgical debridement for acute infection.

Authors:  Giacomo Clerici; Maurizio Caminiti; Vincenzo Curci; Antonella Quarantiello; Ezio Faglia
Journal:  Int Wound J       Date:  2010-06       Impact factor: 3.315

3.  The impact of gender, level of amputation and diabetes on prosthetic fit rates following major lower extremity amputation.

Authors:  Fiona Davie-Smith; Lorna Paul; Natalie Nicholls; Wesley P Stuart; Brian Kennon
Journal:  Prosthet Orthot Int       Date:  2016-07-09       Impact factor: 1.895

4.  Simultaneous transdermal extraction of glucose and lactate from human subjects by reverse iontophoresis.

Authors:  Tak S Ching; Patricia Connolly
Journal:  Int J Nanomedicine       Date:  2008
  4 in total

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