William S Millar1, Angela Lignelli, Michio Hirano. 1. Department of Radiology, New York Presbyterian Hospital, Columbia-Presbyterian Center, 177 Fort Washington Avenue, Milstein Hospital Bldg., Rm. 3-105, New York, NY 10032, USA. wsm8@columbia.edu
Abstract
OBJECTIVE: The purpose of this study was to retrospectively review MR images of the brain in five patients diagnosed with mitochondrial neurogastrointestinal encephalomyopathy. CONCLUSION: Our research supports previously reported findings of confluent abnormal cerebral white matter in patients with mitochondrial neurogastrointestinal encephalomyopathy. In contrast to prior studies, our cohort of five patients showed that involvement of the corpus callosum as well as the capsular white matter, basal ganglia, thalami, midbrain, pons, and cerebellar white matter is not rare and does not preclude the diagnosis of mitochondrial neurogastrointestinal encephalomyopathy.
OBJECTIVE: The purpose of this study was to retrospectively review MR images of the brain in five patients diagnosed with mitochondrial neurogastrointestinal encephalomyopathy. CONCLUSION: Our research supports previously reported findings of confluent abnormal cerebral white matter in patients with mitochondrial neurogastrointestinal encephalomyopathy. In contrast to prior studies, our cohort of five patients showed that involvement of the corpus callosum as well as the capsular white matter, basal ganglia, thalami, midbrain, pons, and cerebellar white matter is not rare and does not preclude the diagnosis of mitochondrial neurogastrointestinal encephalomyopathy.
Authors: Rana Yadak; Peter Sillevis Smitt; Marike W van Gisbergen; Niek P van Til; Irenaeus F M de Coo Journal: Front Cell Neurosci Date: 2017-02-15 Impact factor: 5.505
Authors: S D Roosendaal; T van de Brug; C A P F Alves; S Blaser; A Vanderver; N I Wolf; M S van der Knaap Journal: AJNR Am J Neuroradiol Date: 2021-04-01 Impact factor: 4.966