| Literature DB >> 15149656 |
Xiao-Chun Huang1, Di Zhao, Yue-Wei Guo, Hou-Ming Wu, Li-Ping Lin, Zhong-Hua Wang, Jian Ding, Yong-Shui Lin.
Abstract
A novel polyhydroxy compound with a linear carbon-chain, lingshuiol (1), had been isolated from the cultured marine dinoflagellate Amphidinium sp. Its structure was elucidated by extensive analysis of 2D NMR spectral data. Lingshuiol possessed a powerful cytotoxic activity against A-549 and HL-60 cells in vitro with the IC(50) of 0.21 and 0.23 microM, respectively.Entities:
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Year: 2004 PMID： 15149656 DOI： 10.1016/j.bmcl.2004.04.029
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823