| Literature DB >> 15149649 |
Graham B Jones1, Longfei Xie, Ahmed El-Shafey, Curtis F Crasto, Glenn J Bubley, Anthony V D'Amico.
Abstract
A family of image contrast agent conjugates designed to undergo enzymatic activation has been synthesized. The agents underwent activation both with enzymatically active prostate specific antigen and alpha-chymotrypsin, releasing free fluorophore via cleavage of a three-component system.Entities:
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Year: 2004 PMID： 15149649 DOI： 10.1016/j.bmcl.2004.04.041
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823