Literature DB >> 15148517

[Sclerosing treatment of vascular malformations].

J Cabrera1, P Redondo.   

Abstract

Traditional sclerotherapy with liquid sclerosants has been used for many years in the treatment of venous, lymphatic and low flow vascular malformations; it is efficient only with those vascular malformations of reduced size as a pre or post-operational complement. The use of liquid sclerosants has the limitations of their dilution and progressive inactivation in a great haematic volume, the irregular distribution of the sclerosant on the endothelium, the handling of the sclerosant once injected and its imperceptibility to the echo-Doppler. In their turn, both ethanol and sodium morrhuate - the most habitually employed sclerosants - produce important secondary effects. On the contrary, the use of sclerosants, specifically polidocanol in microfoam form, significantly improves the procedure, since the microfoam displaces the blood instead of mixing and diluting itself in it, thus facilitating an homogeneous distribution of the sclerosant over the endothelial surface. Finally, the echogenicity of the microbubbles, which makes them directly visible, together with their manageable consistency, means that it can be distributed more easily throughout the treated area. We comment on our experience with 50 patients with venous or low flow vascular malformations, treated with this new form of sclerosant. Similarly, the use of OK-432 (picibanil) - as the recommended sclerosant treatment in lymphatic vascular, especially macrocystic, malformations - is reviewed and its protocol given.

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Year:  2004        PMID: 15148517

Source DB:  PubMed          Journal:  An Sist Sanit Navar        ISSN: 1137-6627            Impact factor:   0.829


  3 in total

1.  Sclerotherapy as an esthetic indication in oral vascular malformations: a case series.

Authors:  Brena Rodrigues Manzano; Aloizio Maciel Premoli; Natalia Garcia Santaella; Carla Renata Sanomiya Ikuta; Cássia Maria Fisher Rubira; Paulo Sérgio da Silva Santos
Journal:  An Bras Dermatol       Date:  2019-09-30       Impact factor: 1.896

2.  Sclerotherapy of Vascular Malformations in the Oral Cavity-Minimizing Postoperative Morbidity.

Authors:  Itai Zeevi; Gavriel Chaushu; Michael Alterman; Liat Chaushu
Journal:  Medicina (Kaunas)       Date:  2020-05-22       Impact factor: 2.430

3.  Hot Hypertonic Saline and Compression Device: A Novel Approach in Preventing Severe Hemorrhage during Extirpation of Deep Vascular Malformations of the Face.

Authors:  U Mgbeokwere; O Egwuom
Journal:  Ann Med Health Sci Res       Date:  2012-01
  3 in total

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