| Literature DB >> 15146525 |
R Ian Storer1, Toshiyasu Takemoto, Philip S Jackson, Dearg S Brown, Ian R Baxendale, Steven V Ley.
Abstract
The total synthesis of the cytotoxic antitumour natural product epothilone C has provided a stage for the exploitation and further development of immobilized reagent methods. A stereoselective convergent synthetic strategy was applied, incorporating polymer-supported reagents, catalysts, scavengers and catch-and-release techniques to avoid frequent aqueous work-up and chromatographic purification.Entities:
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Year: 2004 PMID： 15146525 DOI： 10.1002/chem.200305669
Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236