INTRODUCTION: We present a case of unusually rapid tumor progression in a patient with primary sarcomatoid carcinoma of the ureter. CASE REPORT: An 82-year-old female patient underwent total nephroureterectomy for a ureteral tumor that turned out to be a primary sarcomatoid carcinoma of the ureter. After a normal postoperative course, the patient developed a metastatic symptomatic that seemed to have appeared "like an explosion" on the 33rd p. o. day. She died shortly thereafter. CONCLUSION: This is the second case of primary sarcomatoid carcinoma of the ureter published in the literature, a rare and aggressive variant of urothelial carcinoma with a highly malignant potential. As no effective adjuvant treatment has been reported as yet, we recommend mandatory radical excision of the sarcomatoid tumor and early postoperative radiation therapy to increase survival.
INTRODUCTION: We present a case of unusually rapid tumor progression in a patient with primary sarcomatoid carcinoma of the ureter. CASE REPORT: An 82-year-old female patient underwent total nephroureterectomy for a ureteral tumor that turned out to be a primary sarcomatoid carcinoma of the ureter. After a normal postoperative course, the patient developed a metastatic symptomatic that seemed to have appeared "like an explosion" on the 33rd p. o. day. She died shortly thereafter. CONCLUSION: This is the second case of primary sarcomatoid carcinoma of the ureter published in the literature, a rare and aggressive variant of urothelial carcinoma with a highly malignant potential. As no effective adjuvant treatment has been reported as yet, we recommend mandatory radical excision of the sarcomatoid tumor and early postoperative radiation therapy to increase survival.
Authors: Hans-Ullrich Völker; Andreas Zettl; Georg Schön; Vitus Heller; Elmar Heinrich; Andreas Rosenwald; Mathias Handwerker; Hans-Konrad Müller-Hermelink; Alexander Marx; Philipp Ströbel Journal: Virchows Arch Date: 2008-02-12 Impact factor: 4.064