Literature DB >> 15146232

Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation.

Neil J Freedman1, Robert J Lefkowitz.   

Abstract

Antibodies specific for the beta(1)-adrenergic receptor are found in patients with chronic heart failure of various etiologies. From work presented in this issue of the JCI, we can now infer that these antibodies actually contribute to the pathogenesis of chronic heart failure. This commentary discusses mechanisms by which these antibodies may engender cardiomyopathy.

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Year:  2004        PMID： 15146232      PMCID： PMC406535          DOI： 10.1172/JCI21748

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  45 in total

1.  Dilated cardiomyopathy and sudden death resulting from constitutive activation of protein kinase a.

Authors:  C L Antos; N Frey; S O Marx; S Reiken; M Gaburjakova; J A Richardson; A R Marks; E N Olson
Journal:  Circ Res       Date:  2001-11-23       Impact factor: 17.367

Review 2.  Chagas' heart disease.

Authors:  J M Hagar; S H Rahimtoola
Journal:  Curr Probl Cardiol       Date:  1995-12       Impact factor: 5.200

3.  Reduced beta-adrenergic receptor activation decreases G-protein expression and beta-adrenergic receptor kinase activity in porcine heart.

Authors:  P Ping; R Gelzer-Bell; D A Roth; D Kiel; P A Insel; H K Hammond
Journal:  J Clin Invest       Date:  1995-03       Impact factor: 14.808

4.  Autoantibodies against beta-adrenoceptors in human idiopathic dilated cardiomyopathy.

Authors:  C J Limas; I F Goldenberg; C Limas
Journal:  Circ Res       Date:  1989-01       Impact factor: 17.367

5.  Effect of chagasic sera on the rat isolated atrial preparation: immunological, morphological and function aspects.

Authors:  L Sterin-Borda; P M Cossio; M F Gimeno; A L Gimeno; C Diez; R P Laguens; P C Meckert; R M Arana
Journal:  Cardiovasc Res       Date:  1976-11       Impact factor: 10.787

6.  Effect of endothelin-1 and its combination with adenosine on myocardial contractility and myocardial energy metabolism in vivo.

Authors:  M E Beyer; S Nerz; S Kazmaier; H M Hoffmeister
Journal:  J Mol Cell Cardiol       Date:  1995-09       Impact factor: 5.000

7.  Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure.

Authors:  Steven Reiken; Xander H T Wehrens; John A Vest; Alessandro Barbone; Stefan Klotz; Donna Mancini; Daniel Burkhoff; Andrew R Marks
Journal:  Circulation       Date:  2003-05-12       Impact factor: 29.690

8.  Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by beta-adrenergic receptor stimulation and blockade.

Authors:  G Iaccarino; E D Tomhave; R J Lefkowitz; W J Koch
Journal:  Circulation       Date:  1998-10-27       Impact factor: 29.690

Review 9.  What is the role of beta-adrenergic signaling in heart failure?

Authors:  Martin J Lohse; Stefan Engelhardt; Thomas Eschenhagen
Journal:  Circ Res       Date:  2003-11-14       Impact factor: 17.367

10.  Coupling of beta2-adrenoceptor to Gi proteins and its physiological relevance in murine cardiac myocytes.

Authors:  R P Xiao; P Avdonin; Y Y Zhou; H Cheng; S A Akhter; T Eschenhagen; R J Lefkowitz; W J Koch; E G Lakatta
Journal:  Circ Res       Date:  1999 Jan 8-22       Impact factor: 17.367
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  29 in total

Review 1.  The clinical significance of anti-beta-1 adrenergic receptor autoantibodies in cardiac disease.

Authors:  Udi Nussinovitch; Yehuda Shoenfeld
Journal:  Clin Rev Allergy Immunol       Date:  2013-02       Impact factor: 8.667

Review 2.  Receptor function reserve: a new parameter for disease detection.

Authors:  H William Strauss
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-12       Impact factor: 9.236

3.  Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol.

Authors:  Francesca Rochais; Jean-Pierre Vilardaga; Viacheslav O Nikolaev; Moritz Bünemann; Martin J Lohse; Stefan Engelhardt
Journal:  J Clin Invest       Date:  2007-01       Impact factor: 14.808

4.  Selective blockade of nicotinic acetylcholine receptors by pimobendan, a drug for the treatment of heart failure: reduction of catecholamine secretion and synthesis in adrenal medullary cells.

Authors:  Yumiko Toyohira; Tatsuhiko Kubo; Miyabi Watanabe; Yasuhito Uezono; Susumu Ueno; Koji Shinkai; Masato Tsutsui; Futoshi Izumi; Nobuyuki Yanagihara
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2005-02-16       Impact factor: 3.000

5.  Pathophysiological role of autoantibodies against G-protein-coupled receptors in the cardiovascular system.

Authors:  Wolfgang Schulze; Rudolf Kunze; Gerd Wallukat
Journal:  Exp Clin Cardiol       Date:  2005

6.  Stimulatory effect of nobiletin, a citrus polymethoxy flavone, on catecholamine synthesis through Ser19 and Ser40 phosphorylation of tyrosine hydroxylase in cultured bovine adrenal medullary cells.

Authors:  Han Zhang; Nobuyuki Yanagihara; Yumiko Toyohira; Keita Takahashi; Hirohide Inagaki; Noriaki Satoh; Xiaoja Li; Xiumei Goa; Masato Tsutsui; Kojiro Takahaishi
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2013-09-17       Impact factor: 3.000

7.  Provinol inhibits catecholamine secretion from the rat adrenal medulla.

Authors:  Jung-Hee Lee; Yu-Seung Seo; Dong-Yoon Lim
Journal:  Korean J Physiol Pharmacol       Date:  2009-06-30       Impact factor: 2.016

8.  Consequences of unlocking the cardiac myosin molecule in human myocarditis and cardiomyopathies.

Authors:  Adita Mascaro-Blanco; Kathy Alvarez; Xichun Yu; JoAnn Lindenfeld; Leann Olansky; Timothy Lyons; David Duvall; Janet S Heuser; Albina Gosmanova; Carl J Rubenstein; Leslie T Cooper; David C Kem; Madeleine W Cunningham
Journal:  Autoimmunity       Date:  2008-09       Impact factor: 2.815

9.  Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy.

Authors:  Tielin Zhou; Jing Li; Peiquan Zhao; Huijuan Liu; Deyong Jia; Hao Jia; Lin He; Yong Cang; Sharon Boast; Yi-Han Chen; Hélène Thibault; Marielle Scherrer-Crosbie; Stephen P Goff; Baojie Li
Journal:  Proc Natl Acad Sci U S A       Date:  2015-12-07       Impact factor: 11.205

10.  Pharmacokinetics and Safety of Single Intravenous Doses of JNJ-54452840, an Anti-β1-Adrenergic Receptor Antibody Cyclopeptide, in Healthy Male Japanese and Caucasian Participants.

Authors:  Ivo P Nnane; Alexei H Plotnikov; Gary Peters; Maureen Johnson; Clare Kojak; Apinya Vutikullird; Jay Ariyawansa; Ronald De Vries; Brian E Davies
Journal:  Clin Pharmacokinet       Date:  2016-02       Impact factor: 6.447
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